Prof. Marco Stampanoni Profile

Prof. Marco Stampanoni

Head of X-ray Tomography Group at ETH Zurich

SPIE Involvement:

Author

Publications (29)

Proceedings Article | 18 October 2022 Open Access

Iterative grating interferometry-based phase-contrast CT reconstruction with a data-driven denoising prior

Stefano van Gogh, Subhadip Mukherjee, Michał Rawlik, Zhentian Wang, Jinqiu Xu, Zsuzsanna Varga, Carola-Bibiane Schönlieb, Marco Stampanoni

Proceedings Volume 12304, 1230417 (2022) https://doi.org/10.1117/12.2646437

KEYWORDS: Reconstruction algorithms, Denoising, X-rays, Interferometry, Breast, X-ray computed tomography, Neural networks, Visibility, Refraction, Phase interferometry

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Proceedings Article | 9 September 2019 Paper

X-ray Fourier ptychography for out-of-focus measurements

Klaus Wakonig, Ana Diaz, Sabina Chiriotti, Anna Bergamaschi, Anne Bonnin, Marco Stampanoni, Andreas Menzel

Proceedings Volume 11112, 111120I (2019) https://doi.org/10.1117/12.2528905

KEYWORDS: X-rays, Objectives, X-ray imaging, Sensors, Microscopes, Zone plates, Image resolution, Image quality, Hard x-rays, Phase contrast, Alignment procedures, Quantitative analysis, Detector development

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Proceedings Article | 2 May 2017 Presentation

Design of a sensitive grating-based phase contrast mammography prototype (Conference Presentation)

Carolina Arboleda Clavijo, Zhentian Wang, Thomas Köhler, Udo van Stevendaal, Gerhard Martens, Matthias Bartels, Pablo Villanueva-Perez, Ewald Roessl, Marco Stampanoni

Proceedings Volume 10132, 1013218 (2017) https://doi.org/10.1117/12.2253875

KEYWORDS: Prototyping, Mammography, Phase contrast, Breast, Tissues, Interferometers, Signal to noise ratio, Visibility, Data modeling, Optical design

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Proceedings Article | 27 March 2017 Paper

High-aspect ratio silicon structures by displacement Talbot lithography and Bosch etching

Konstantins Jefimovs, Lucia Romano, Joan Vila-Comamala, Matias Kagias, Zhentian Wang, Li Wang, Christian Dais, Harun Solak, Marco Stampanoni

Proceedings Volume 10146, 101460L (2017) https://doi.org/10.1117/12.2258007

KEYWORDS: Lithography, Semiconducting wafers, Photomasks, Lithographic illumination, Reactive ion etching, Silicon, Phase contrast, X-ray imaging, Etching, Optical lithography, X-rays, Photoresist materials, Chromium

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Proceedings Article | 16 June 2014 Paper

Performance of X-ray grating interferometry at high energy

Matteo Abis, Thomas Thüring, Marco Stampanoni

Proceedings Volume 9033, 903354 (2014) https://doi.org/10.1117/12.2041270

KEYWORDS: Visibility, Interferometers, X-rays, Interferometry, Optical design, Sensors, Refraction, Absorption, Reconstruction algorithms, Beam splitters

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Proceedings Article | 19 March 2014 Paper

Comparison of propagation- and grating-based x-ray phase-contrast imaging techniques with a liquid-metal-jet source

T. Zhou, U. Lundström, Thomas Thüring, S. Rutishauser, D. Larsson, M. Stampanoni, C. David, H. Hertz, A. Burvall

Proceedings Volume 9033, 903353 (2014) https://doi.org/10.1117/12.2043417

KEYWORDS: Absorption, Sensors, X-ray imaging, Monte Carlo methods, X-rays, Signal to noise ratio, Positron emission tomography, Breast, Tissues, Wave propagation

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Proceedings Article | 6 March 2013 Paper

Compact hard X-ray grating interferometry for table top phase contrast micro CT

T. Thüring, S. Hämmerle, S. Weiss, J. Nüesch, J. Meiser, J. Mohr, C. David, M. Stampanoni

Proceedings Volume 8668, 866813 (2013) https://doi.org/10.1117/12.2006865

KEYWORDS: Interferometers, X-ray computed tomography, X-rays, Phase contrast, Sensors, Imaging systems, Visibility, Absorption, Interferometry, Image resolution

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Proceedings Article | 6 March 2013 Paper

Reconstruction method incorporating the object-position dependence of visibility loss in dark-field imaging

Udo van Stevendaal, Zhentian Wang, Thomas Köhler, Gerhard Martens, Marco Stampanoni, Ewald Roessl

Proceedings Volume 8668, 86680Z (2013) https://doi.org/10.1117/12.2006711

KEYWORDS: Visibility, Reconstruction algorithms, Signal attenuation, X-rays, Absorption, Scattering, X-ray computed tomography, X-ray imaging, Fluctuations and noise, Scanners

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Proceedings Article | 17 October 2012 Paper

Multi-scale image fusion for x-ray grating-based mammography

Xiaolei Jiang, Li Zhang, Zhentian Wang, Marco Stampanoni

Proceedings Volume 8506, 850612 (2012) https://doi.org/10.1117/12.929625

KEYWORDS: Image fusion, X-rays, Principal component analysis, Mammography, X-ray imaging, Signal attenuation, Denoising, Spatial frequencies, Phase contrast, Image quality

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Proceedings Article | 24 February 2012 Paper

Image fusion algorithm for differential phase contrast imaging

Ewald Roessl, Thomas Koehler, Udo van Stevendaal, Gerhard Martens, Nik Hauser, Zhentian Wang, Marco Stampanoni

Proceedings Volume 8313, 831354 (2012) https://doi.org/10.1117/12.911255

KEYWORDS: Signal attenuation, Image fusion, Phase contrast, X-rays, Refractive index, Algorithm development, Breast, Medical imaging, Fusion energy, Tissues

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Proceedings Article | 17 March 2011 Paper

Towards x-ray differential phase contrast imaging on a compact setup

T. Thüring, P. Modregger, B. Pinzer, Z. Wang, S. Rutishauser, C. David, T. Grund, J. Kenntner, M. Stampanoni

Proceedings Volume 7961, 79611G (2011) https://doi.org/10.1117/12.877218

KEYWORDS: Visibility, X-rays, Absorption, Phase contrast, Interferometers, X-ray imaging, Diffraction gratings, Sensors, X-ray computed tomography, Scanners

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Proceedings Article | 12 February 2011 Paper

Design and realization of a spectroscopic optical coherence tomography system for medical applications

Patrick Steiner, Christoph Meier, Volker Koch, Marco Stampanoni

Proceedings Volume 7889, 78892I (2011) https://doi.org/10.1117/12.873785

KEYWORDS: Absorption, Optical coherence tomography, Spectroscopy, Signal attenuation, Liquids, Scattering, Interfaces, Electronic filtering, Optical spectroscopy, Light sources

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Proceedings Article | 20 September 2010 Paper

Fast reconstruction algorithm dealing with tomography artifacts

Federica Marone, Beat Münch, Marco Stampanoni

Proceedings Volume 7804, 780410 (2010) https://doi.org/10.1117/12.859703

KEYWORDS: Reconstruction algorithms, Tomography, Fourier transforms, Data acquisition, Convolution, Image filtering, Sensors, Scintillators, Image quality standards, Synchrotron technology

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Proceedings Article | 20 September 2010 Paper

Deciphering complex, functional structures with synchrotron-based absorption and phase contrast tomographic microscopy

M. Stampanoni, J. Reichold, B. Weber, D. Haberthür, J. Schittny, J. Eller, F. Büchi, F. Marone

Proceedings Volume 7804, 78040L (2010) https://doi.org/10.1117/12.860208

KEYWORDS: Lung, Tomography, Microscopy, Phase contrast, 3D modeling, Nanoparticles, Absorption, Tissues, Brain, Visualization

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Proceedings Article | 18 September 2008 Paper

X-ray tomographic microscopy at TOMCAT

F. Marone, C. Hintermüller, S. McDonald, R. Abela, G. Mikuljan, A. Isenegger, M. Stampanoni

Proceedings Volume 7078, 707822 (2008) https://doi.org/10.1117/12.803147

KEYWORDS: Tomography, Phase contrast, X-ray microscopy, Absorption, X-rays, Microscopy, Data acquisition, Reconstruction algorithms, Hard x-rays, Synchrotrons

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Proceedings Article | 17 September 2008 Paper

Hierarchical multimodal tomographic x-ray imaging at a superbend

M. Stampanoni, F. Marone, G. Mikuljan, K. Jefimovs, P. Trtik, J. Vila-Comamala, C. David, R. Abela

Proceedings Volume 7078, 70780V (2008) https://doi.org/10.1117/12.793759

KEYWORDS: Tomography, X-rays, Sensors, Microscopes, X-ray microscopy, Phase contrast, Zone plates, X-ray imaging, Absorption, Optical spheres

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Proceedings Article | 12 March 2008 Paper

Synchrotron radiation CT methods for 3D quantitative assessment of mechanically relevant ultrastructural properties in murine bone

Philipp Schneider, Romain Voide, Marco Stampanoni, Ralph Müller

Proceedings Volume 6916, 691619 (2008) https://doi.org/10.1117/12.772668

KEYWORDS: Bone, Tissues, Computed tomography, Mechanics, X-ray computed tomography, Tomography, Synchrotron radiation, Calcium, 3D image processing, Nondestructive evaluation

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Proceedings Article | 6 April 2007 Paper

Computer-based analysis of microvascular alterations in a mouse model for Alzheimer's disease

Stefan Heinzer, Ralph Müller, Marco Stampanoni, Rafael Abela, Eric Meyer, Alexandra Ulmann-Schuler, Thomas Krucker

Proceedings Volume 6511, 651104 (2007) https://doi.org/10.1117/12.708869

KEYWORDS: Visualization, Image segmentation, Visual analytics, 3D image processing, Databases, Brain, Neuroimaging, Alzheimer's disease, Image resolution, Data storage

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Proceedings Article | 7 September 2006 Paper

Assessment of murine bone ultrastructure using synchrotron light: towards nano-computed tomography

Philipp Schneider, Romain Voide, Martin Stauber, Marco Stampanoni, Leah Rae Donahue, Peter Wyss, Urs Sennhauser, Ralph Müller

Proceedings Volume 6318, 63180C (2006) https://doi.org/10.1117/12.679427

KEYWORDS: Bone, Tissues, Tomography, Spatial resolution, X-rays, Visualization, Light sources, Image segmentation, 3D image processing, Synchrotrons

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Proceedings Article | 7 September 2006 Paper

Trends in synchrotron-based tomographic imaging: the SLS experience

M. Stampanoni, A. Groso, A. Isenegger, G. Mikuljan, Q. Chen, A. Bertrand, S. Henein, R. Betemps, U. Frommherz, P. Böhler, D. Meister, M. Lange, R. Abela

Proceedings Volume 6318, 63180M (2006) https://doi.org/10.1117/12.679497

KEYWORDS: Tomography, Absorption, X-rays, Phase contrast, X-ray microscopy, Crystals, Laser sintering, Microscopy, Photons, Optical components

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Proceedings Article | 13 March 2006 Paper

Functional microimaging: an integrated approach for advanced bone biomechanics and failure analysis

Romain Voide, G. van Lenthe, Philipp Schneider, Philipp Thurner, Peter Wyss, Urs Sennhauser, Marco Stampanoni, Martin Stauber, Jess Snedeker, Ralph Müller

Proceedings Volume 6143, 61430X (2006) https://doi.org/10.1117/12.650485

KEYWORDS: Bone, Visualization, Head, Tomography, Image resolution, Nondestructive evaluation, 3D image processing, Failure analysis, High speed cameras, Neck

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Biomechanical testing is the gold standard to determine bone competence, and has been used extensively. Direct mechanical testing provides detailed information on overall bone mechanical and material properties, but fails in revealing local properties such as local deformations and strains or quantification of fracture progression. Therefore, we incorporated several imaging methods in our mechanical setups in order to get a better insight into bone deformation and failure characteristics. Our aim was to develop an integrative approach for hierarchical investigation of bone, working at different scales of resolution ranging from the whole bone to its ultrastructure. At a macroscopic level, we used high-resolution and high-speed cameras which drastically increased the amount of information obtained from a biomechanical bone test. The new image data proved especially important when dealing with very small bones such as the murine femur. Here the feedback of the camera in the process of aligning and positioning the samples is indispensable for reproducibility. In addition, global failure behavior and fracture initiation can now be visualized with high temporal resolution. At a microscopic level, bone microstructure, i.e. trabecular architecture and cortical porosity, are known to influence bone strength and failure mechanisms significantly. For this reason, we developed an image-guided failure assessment technique, also referred to as functional microimaging, allowing direct time-lapsed 3D visualization and computation of local displacements and strains for better quantification of fracture initiation and progression at the microscopic level. While the resolution of typical desktop micro-computed tomography is around a few micrometers, highly brilliant X-rays from synchrotron radiation permit to explore the nanometer world. This allowed, for the first time, to uncover fully nondestructively the 3D ultrastructure of bone including vascular and cellular structures and to investigate their role in development of bone microcracks in an unprecedented resolution. We conclude that functional microimaging, i.e. the combination of biomechanical testing with non-destructive 3D imaging and visualization are extremely valuable in studying bone failure mechanisms. Functional investigation of microcrack initiation and propagation will lead to a better understanding of the relative contribution of bone mass and bone quality to bone competence.

Proceedings Article | 26 October 2004 Paper

Hierarchical bioimaging and quantification of vasculature in disease models using corrosion casts and microcomputed tomography

Stefan Heinzer, Thomas Krucker, Marco Stampanoni, Rafael Abela, Eric Meyer, Alexandra Schuler, Philipp Schneider, Ralph Muller

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.559514

KEYWORDS: Tomography, Imaging systems, Corrosion, Brain, Data acquisition, Scanning electron microscopy, X-rays, Software development, Capillaries, Image resolution

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Proceedings Article | 26 October 2004 Paper

New developments in synchrotron-based microtomography

Marco Stampanoni, Rafael Abela, Gunther Borchert, Bruce Patterson

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.557870

KEYWORDS: Tomography, X-rays, Crystals, Laser sintering, Phase contrast, Diffraction, Spatial resolution, X-ray microscopy, Scintillators, Charge-coupled devices

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Proceedings Article | 26 October 2004 Paper

Functional micro-imaging of soft and hard tissue using synchrotron light

Philipp Thurner, Peter Wyss, Romain Voide, Martin Stauber, Bert Muller, Marco Stampanoni, Jeffrey Hubbell, Ralph Muller, Urs Sennhauser

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.559515

KEYWORDS: Bone, Tomography, Tissues, Scanning electron microscopy, 3D image processing, 3D visualizations, Gold, Synchrotron radiation, Failure analysis, Positron emission tomography

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Proceedings Article | 26 October 2004 Paper

Hard x-ray phase imaging and tomography with a grating interferometer

Timm Weitkamp, Ana Diaz, Bernd Nohammer, Franz Pfeiffer, Torben Rohbeck, Peter Cloetens, Marco Stampanoni, Christian David

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.569643

KEYWORDS: Absorption, Tomography, Interferometers, Sensors, Wavefronts, Phase imaging, X-rays, Silicon, Signal detection, Interferometry

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Proceedings Article | 18 October 2004 Paper

Moiré interferometry formulas for hard x-ray wavefront sensing

Timm Weitkamp, A. Diaz, Bernd Nohammer, Franz Pfeiffer, Marco Stampanoni, Eric Ziegler, Christian David

Proceedings Volume 5533, (2004) https://doi.org/10.1117/12.559695

KEYWORDS: Wavefronts, Absorption, Fringe analysis, Sensors, Hard x-rays, Wavefront sensors, Deflectometry, Interferometers, X-rays, Wavefront distortions

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Proceedings Article | 6 May 2004 Paper

Soft-tissue and phase-contrast imaging at the Swiss Light Source

Philipp Schneider, Nishant Mohan, Marco Stampanoni, Ralph Muller

Proceedings Volume 5368, (2004) https://doi.org/10.1117/12.533716

KEYWORDS: Bone, Tissues, Absorption, Phase contrast, X-rays, Light sources, Corrosion, Head, Imaging systems, Tomography

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Recent results show that bone vasculature is a major contributor to local tissue porosity, and therefore can be directly linked to the mechanical properties of bone tissue. With the advent of third generation synchrotron radiation (SR) sources, micro-computed tomography (μCT) with resolutions in the order of 1 μm and better has become feasible. This technique has been employed frequently to analyze trabecular architecture and local bone tissue properties, i.e. the hard or mineralized bone tissue. Nevertheless, less is known about the soft tissues in bone, mainly due to inadequate imaging capabilities. Here, we discuss three different methods and applications to visualize soft tissues. The first approach is referred to as negative imaging. In this case the material around the soft tissue provides the absorption contrast necessary for X-ray based tomography. Bone vasculature from two different mouse strains was investigated and compared qualitatively. Differences were observed in terms of local vessel number and vessel orientation. The second technique represents corrosion casting, which is principally adapted for imaging of vascular systems. The technique of corrosion casting has already been applied successfully at the Swiss Light Source. Using the technology we were able to show that pathological features reminiscent of Alzheimer’s disease could be distinguished in the brain vasculature of APP transgenic mice. The third technique discussed here is phase contrast imaging exploiting the high degree of coherence of third generation synchrotron light sources, which provide the necessary physical conditions for phase contrast. The in-line approach followed here for phase contrast retrieval is a modification of the Gerchberg-Saxton-Fienup type. Several measurements and theoretical thoughts concerning phase contrast imaging are presented, including mathematical phase retrieval. Although up-to-now only phase images have been computed, the approach is now ready to retrieve the phase for a large number of angular positions of the specimen allowing application of holotomography, which is the three-dimensional reconstruction of phase images.