Aging alterations in dermal blood vessels have been investigated using Optical Coherence Tomography Angiography (OCTA). However, classifying the vessel’s type was previously limited. In this study, we focused on diameter-dependent vascular alterations in facial skin with age, developing 3D analytical methods to the OCTA data with removing tail-artifact. As a result, it was found that the number of micro-vessels, defined at 20–39 microns, decreased with age, which was inversely true for thick vessels (160–179 micron diameter). Our results suggest that the aging degree of dermal vessels may be uniquely assessed by the diameter-dependent vascular alterations using the OCTA.
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