Prof. Hirofumi Kadono Profile

Prof. Hirofumi Kadono

Professor at Saitama Univ

SPIE Involvement:

Conference Program Committee | Author

Publications (38)

Proceedings Article | 20 June 2024 Presentation + Paper

Fast and reliable micro bioassay techniques based on biospeckle for swift water assessment using plankton

Arti Devi, Hirofumi Kadono, Uma Maheswari Rajagopalan

Proceedings Volume 13008, 1300804 (2024) https://doi.org/10.1117/12.3022436

KEYWORDS: Microorganisms, Iron, Zinc, Toxicity, Biospeckle, Control systems, Metals, Tolerancing, Organisms, Imaging systems

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Proceedings Article | 18 June 2024 Presentation + Paper

Biospeckle optical coherence tomography in visualizing the repetitive hot-cold response of skin age related difference

Ryosuke Nakasako, Jun Yamada, Takahiro Kono, Hirofumi Kadono, Uma Maheswari Rajagopalan

Proceedings Volume 13010, 130100R (2024) https://doi.org/10.1117/12.3021703

KEYWORDS: Optical coherence tomography, Skin, Biospeckle, Visualization, Blood vessels, Elasticity, Temperature metrology, Tissues, Speckle, Body temperature

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Proceedings Article | 18 June 2024 Presentation + Paper

Biospeckle optical coherence tomography (bOCT) reveals the size-dependent impacts of micro and nano metal oxide particles on lentil seed’s internal activity

Lavista Tyagi, Hirofumi Kadono, Uma Maheswari Rajagopalan

Proceedings Volume 13010, 130100T (2024) https://doi.org/10.1117/12.3022190

KEYWORDS: Zinc oxide, Optical coherence tomography, Biospeckle, Particles, Nanoparticles, Metal oxides, Nanomaterials, Zinc, Industry, Computed tomography

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Nanoparticles (NPs) have become more prevalent in the agricultural, industrial, and medicinal fields. There is rising interest in how nanomaterials interact with plants since they influence plants and seeds differently depending on their size, shape, and dose. The techniques to monitor the response of plants to NPs are crucial since the effects of nanomaterials on seed germination and plant growth are uncertain. In this study, a highly sensitive, real-time, non-invasive novel technique called Biospeckle optical coherence tomography (bOCT) is used to examine the size-dependent impact of metal oxides NPs and microparticles (MPs) like Zinc Oxide (ZnO) with a size less than 50 nm, and 45μm and Titanium dioxide (TiO₂) with a size 21 nm and <5μm at concentrations of 25mg/L and 100mg/L on the internal activity of lentil seeds before germination. The results showed that ZnO NPs had an adverse effect at both higher and lower concentrations on the internal activity of lentil seeds, while MPs of 45μm had significantly positive effects even with higher concentrations. However, TiO₂ MPs and NPs showed a significant positive effect on Lentil seed’s internal activity at both concentrations in comparison to control. The proposed method was able to detect the response of Lentil seed’s internal activities to different concentrations and sizes of metal oxides NPs and MPs at an early stage just after 5 hours of exposure before the germination. On the other hand, the conventional physiological methods required a week for the effects to be detected, and the results from bOCT after 5 hours were consistent with those obtained by conventional measures. Because of the non-invasive nature of bOCT, requiring only tens of seconds of measurement with an intact. Furthermore, the technique is capable of monitoring internal biological activities while the conventional OCT monitors just structural images. It has not only the potential to screen but could also constantly monitor long-term changes, thus contributing to the study of the effects of nanomaterials on plants.

Proceedings Article | 22 May 2023 Presentation + Paper

Biospeckle optical coherence tomography reveals the mitigation of the harmful effects of heavy metal zinc in combination with polyethylene microplastics in lentil seeds

Y. Sanath De Silva, Uma Maheswari Rajagopalan, Hirofumi Kadono

Proceedings Volume 12327, 123270P (2023) https://doi.org/10.1117/12.2642702

KEYWORDS: Zinc, Optical coherence tomography, Biospeckle, Polyethylene

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Proceedings Article | 7 March 2023 Presentation + Paper

Fast and reliable micro-bioassay technique based on biospeckle

Arti Devi, Hirofumi Kadono, Uma Maheswari Rajagopalan

Proceedings Volume 12377, 123770F (2023) https://doi.org/10.1117/12.2651049

KEYWORDS: Biospeckle, Toxicity, Microorganisms, Industrial chemicals, Speckle pattern, Microscopes, Imaging systems, Chemical analysis, CCD cameras, Statistical analysis

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Proceedings Article | 7 March 2023 Presentation + Paper

Monitoring the effects of heavy metal (Cu) on aquatic plant (Myriophyllum) using biospeckle optical coherence tomography and statistical interferometry technique

Zulpikar Muhammat, Hirofumi Kadono, Uma Maheswari Rajagopalan

Proceedings Volume 12377, 123770A (2023) https://doi.org/10.1117/12.2651069

KEYWORDS: Copper, Metals, Optical coherence tomography, Biospeckle, National Ignition Facility, Pigments, Optical sensing, Interferometry, Hydrogen, Computed tomography

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Heavy metals are one of the important components of water pollution. Heavy metals such as copper, zinc and cobalt are essential for the growth of living organisms as micronutrients. However, copper above critical levels can pose serious problems for the environment and human health. The biospeckle observed in OCT have the potential to map dynamic activities inside the plants. We propose biospeckle optical coherence tomography (bOCT) and demonstrate that the technique can monitor biological activity in plants. In bOCT, the temporal speckle contrast variation of the OCT reflection signal is used as a parameter to characterize the internal activities of the aquatic plant (Myriophyllum). Plant stems were observed using the bOCT technique after 7 days of exposure to copper solutions of three different copper concentrations to 0, 30, 100 mg/l. In addition, statistical Interferometry Technique (SIT) system that is also a very sensitive optical measurement technique developed in our lab. SIT enables the direct observation of short-term displacement or extension / shrinkage of plant surface with precision of nanometer scale and on a time scale of seconds. Compared with the bOCT technique, it takes short time. It does not require 7 days of exposure time. In just 3 hours of experiment time, we observed that the plants were receiving heavy metal stress in the copper solution. Under the same heavy metal exposure conditions (7 days), enzyme activities in plants were also measured and analyzed to demonstrate the reliability of our two laser measurement techniques. It can be seen that the increase of copper solution has a significant effect on the activity of plants. It was not possible to observe the effects of 7 days of heavy metal exposure on plants by measuring their length or the color of their leaves. Compared with traditional bioassay methods, SIT technology is the fastest, followed by bOCT technology. Both technologies are advanced and can be used as a new method for the determination of plant bioactivity.

Proceedings Article | 7 March 2023 Presentation + Paper

Evaluation of sub-nanometric plant growth activities under far-red light illumination using Statistical Interferometry Technique (SIT)

Kai Yabuki, Hirofumi Kadono

Proceedings Volume 12377, 123770B (2023) https://doi.org/10.1117/12.2650613

KEYWORDS: Light sources and illumination, Speckle, Light emitting diodes, Optical interferometry, Reflection, CCD cameras, Speckle pattern, Speckle interferometry, Laser interferometry

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Proceedings Article | 7 March 2023 Presentation + Paper

Laser biospeckle based novel method in the evaluation of far-red light effects on plant growth

Hibiki Igarashi, Kairi Takemura, Takahiro Kono, Hirofumi Kadono, Jun Yamada, Uma Maheswari Rajagopalan

Proceedings Volume 12377, 123770C (2023) https://doi.org/10.1117/12.2649031

KEYWORDS: Biospeckle, Light sources and illumination, Laser irradiation, Biological samples, Speckle pattern, Vacuum chambers, Tissues, Scattered light, Climate change, CMOS cameras

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Proceedings Article | 19 May 2022 Presentation + Paper

Biospeckle Optical Coherence Tomography (bOCT) reveals variable effects of acid mine drainage (AMD) on monocot and dicot seed germination

Danyang Li, Uma Maheswari Rajagopalan, Hirofumi Kadono, Yakdehige Sanath Kumara De Silva

Proceedings Volume 12147, 121470D (2022) https://doi.org/10.1117/12.2621440

KEYWORDS: Optical coherence tomography, Mining, Visualization, Superluminescent diodes, Mirrors, Minerals, Mechanical engineering, Environmental sensing, Agriculture

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Proceedings Article | 19 May 2022 Presentation + Paper

Optical screening method to observe the biological activities of lentil (Lens culinaris) seeds quantitatively under the exposure of polyethylene microplastics (PEMPs) using ultrahigh accurate biospeckle optical coherence tomography

Y. Sanath K. De Silva, Uma Maheswari Rajagopalan, Danyang Li, Hirofumi Kadono

Proceedings Volume 12147, 121470C (2022) https://doi.org/10.1117/12.2620176

KEYWORDS: Optical coherence tomography, Visualization, Biomedical optics, Particles, Nondestructive evaluation, In vivo imaging, Ecosystems, Botany, Agriculture, Thin film coatings

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Proceedings Article | 2 March 2022 Poster + Presentation + Paper

Functional optical coherence tomography in the study of plant-sound interactions

Ryotaro Wakumoto, Takahiro Kono, Hirofumi Kadono, Jun Yamada, Uma Maheswari Rajagopalan

Proceedings Volume 11958, 119580G (2022) https://doi.org/10.1117/12.2607538

KEYWORDS: Optical coherence tomography, Scattering, Mirrors, Light scattering, Laser scattering, Mie scattering, Speckle, Reflectivity, Photonics, Tissues

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Proceedings Article | 2 March 2022 Presentation + Paper

Application of laser speckles and deep learning in discrimination of supermicroplastics and zooplanktons

Daiki Endo, Takahiro Kono, Yoshikazu Koike, Hirofumi Kadono, Jun Yamada, Uma Rajagopalan

Proceedings Volume 11950, 1195007 (2022) https://doi.org/10.1117/12.2609366

KEYWORDS: Speckle, Particles, Video, Speckle pattern, Light scattering, Organisms, Statistical analysis, Image classification

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Proceedings Article | 2 April 2020 Presentation + Paper

Evaluation of germination ability of seeds at different temperatures by biospeckle optical coherence tomography

Yiheng Lim, Hirofumi Kadono

Proceedings Volume 11363, 113630B (2020) https://doi.org/10.1117/12.2555008

KEYWORDS: Optical coherence tomography, Speckle, Speckle pattern, Visualization, Speckle analysis

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Proceedings Article | 20 February 2020 Paper

Ultrahigh accurate statistical interferometric technique utilizing uniformity of speckle phase in the study of plant physiology

Uma Maheswari Rajagopalan, Hirofumi Kadono, Mahjabin Kabir

Proceedings Volume 11238, 1123815 (2020) https://doi.org/10.1117/12.2543973

KEYWORDS: Speckle, Interferometers, Interferometry, Speckle pattern, Natural surfaces, Laser scattering, Physiology, Light scattering, Environmental sensing

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Proceedings Article | 1 March 2019 Paper

Monitor biological activities in seed germination by biospeckle optical coherence tomography

Yiheng Lim, Kosuke Funada, Hirofumi Kadono

Proceedings Volume 10877, 108770B (2019) https://doi.org/10.1117/12.2509725

KEYWORDS: Speckle, Optical coherence tomography, Visualization, Tissues, Biological research, Inspection

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Crop yields are frequently affected by the vigor of seeds. Although germination tests and vigor tests are performed on sampled seeds to ensure the quality of seeds, selection of crops is based on the appearance or physical properties of roots and shoots of seedlings. Monitoring of the biological activities of seed by biospeckle Optical Coherence Tomography (OCT) was proposed for the selection of seeds. Biospeckle OCT used speckle contrast, which is defined by the ratio of standard deviation to mean value, of the temporal fluctuation of OCT intensities to indicate the biological activities of seeds. Seeds of pea were germinated for the experiment. As a comparison of the level of biological activities, some seeds were boiled to terminate the biological activities. Multiple OCT scans at the same positions on the seeds were obtained for the analysis of biospeckle. The speckle contrast was calculated for each pixel of OCT intensities at each measurement. Increased speckle contrast was observed in the seeds even before the radicle emerged. Low speckle contrast was observed in the boiled seeds. As a conclusion, the speckle contrast of OCT intensities indicated biological activities of seeds in the process of germination. It has the potential to indicate if a seed is dead or alive in an early stage of germination for the purpose of seed selection.Crop yields are frequently affected by the vigor of seeds. Although germination tests and vigor tests are performed on sampled seeds to ensure the quality of seeds, selection of crops is based on the appearance or physical properties of roots and shoots of seedlings. Monitoring of the biological activities of seed by biospeckle Optical Coherence Tomography (OCT) was proposed for the selection of seeds. Biospeckle OCT used speckle contrast, which is defined by the ratio of standard deviation to mean value, of the temporal fluctuation of OCT intensities to indicate the biological activities of seeds. Seeds of pea were germinated for the experiment. As a comparison of the level of biological activities, some seeds were boiled to terminate the biological activities. Multiple OCT scans at the same positions on the seeds were obtained for the analysis of biospeckle. The speckle contrast was calculated for each pixel of OCT intensities at each measurement. Increased speckle contrast was observed in the seeds even before the radicle emerged. Low speckle contrast was observed in the boiled seeds. As a conclusion, the speckle contrast of OCT intensities indicated biological activities of seeds in the process of germination. It has the potential to indicate if a seed is dead or alive in an early stage of germination for the purpose of seed selection.

SPIE Journal Paper | 25 July 2016

Monitoring of growth dynamics of plants under the influence of cadmium using a highly sensitive interferometry technique

Kokge Thilini Kanchana Muthumali De Silva, Uma Maheswari Rajagopalan, Hirofumi Kadono

OE, Vol. 55, Issue 12, 121718, (July 2016) https://doi.org/10.1117/12.10.1117/1.OE.55.12.121718

KEYWORDS: Cadmium, National Ignition Facility, Interferometry, Metals, Speckle, Computed tomography, Optical engineering, Statistical analysis, CCD cameras, Speckle pattern

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Proceedings Article | 24 August 2015 Paper

Monitoring of cadmium influence on ultra short-term growth dynamics of plants using a highly sensitive interferometric technique, SIT

Kokge De Silva, Hirofumi Kadono

Proceedings Volume 9660, 96600A (2015) https://doi.org/10.1117/12.2196866

KEYWORDS: Cadmium, National Ignition Facility, Interferometry, Metals, Speckle, Speckle pattern, Toxicity, Photosynthesis, Tolerancing, Light scattering

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Proceedings Article | 24 August 2015 Paper

Observation of drying process of multilayered paint using fOCT based on dynamic speckles

T. Fukai, H. Kadono

Proceedings Volume 9660, 966010 (2015) https://doi.org/10.1117/12.2196861

KEYWORDS: Particles, Multilayers, Speckle, Optical coherence tomography, Interfaces, Glasses, Scattering, Image processing, Signal processing, Resistance

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Proceedings Article | 17 May 2013 Paper

Optical coherence tomography biospeckle imaging for fast monitoring varying surface responses of a plant leaf under ozone stress

L. K. Srimal, H. Kadono, U. Rajagopalan

Proceedings Volume 8881, 88810H (2013) https://doi.org/10.1117/12.2031062

KEYWORDS: Ozone, Optical coherence tomography, Coherence imaging, Ions, Mirrors, Imaging systems, Data acquisition, Humidity, In vivo imaging, Signal detection

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Proceedings Article | 14 September 2010 Paper

Measurement of vegetable growth by laser-speckle correlation

Koichi Kobayashi, Hirofumi Kadono, Ichirou Yamaguchi

Proceedings Volume 7387, 73870G (2010) https://doi.org/10.1117/12.871220

KEYWORDS: Speckle, Charge-coupled devices, Coating, Metals, Laser marking, Speckle pattern, Optical correlators, Semiconductor lasers, Reflectivity, Glasses

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Proceedings Article | 14 September 2010 Paper

Phase shift error compensation method for digital holography using statistics of speckle field

H. Kadono, M. Kataoka, V. Madjarova

Proceedings Volume 7387, 738706 (2010) https://doi.org/10.1117/12.871117

KEYWORDS: Phase shifts, Speckle, Error analysis, Digital holography, Phase shifting, Interferometry, Holographic interferometry, Holograms, 3D image reconstruction, CCD cameras

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Proceedings Article | 18 June 2007 Paper

Stress behavior of ball grid array (BGA) studied by dynamic electronic speckle pattern interferometry (DESPI)

Violeta Dimitrova Madjarova, Satoru Toyooka, Hiroyuki Chida, Hirofumi Kadono

Proceedings Volume 6616, 66162R (2007) https://doi.org/10.1117/12.726094

KEYWORDS: Speckle pattern, Interferometry, Speckle, Ferroelectric materials, Data processing, Mirrors, Modulation, Phase shift keying, Fringe analysis, Image filtering

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Proceedings Article | 15 September 2006 Paper

Statistical interferometry and application to monitoring of biological activity of plants

Hirofumi Kadono, Naoya Shimizu, Satoru Toyooka

Proceedings Volume 6341, 634119 (2006) https://doi.org/10.1117/12.695360

KEYWORDS: Speckle, Interferometry, Ozone, Pollution, Speckle pattern, Wavefronts, Environmental monitoring, Beam splitters, Biomedical optics, Phase interferometry

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Proceedings Article | 7 October 2005 Paper

Phase shifting phase contrast interferometer using a dye-doped liquid-crystal self-aligning phase modulator

Hirofumi Kadono, Kazunori Ohno, Satoru Toyooka

Proceedings Volume 5947, 59470L (2005) https://doi.org/10.1117/12.622928

KEYWORDS: Phase shift keying, Phase modulation, Phase measurement, Phase contrast, Absorption, Liquid crystals, Diffraction, Imaging systems, Modulators, Phase shifting

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Proceedings Article | 19 November 2003 Paper

Monitoring of biological activity of plant using difference-image of biospeckle

Hirofumi Kadono, Genyoh Takahashi, Satoru Toyooka

Proceedings Volume 4829, (2003) https://doi.org/10.1117/12.527504

KEYWORDS: Pollution, Speckle, Speckle pattern, Ozone, Eye, Veins, Environmental monitoring, Light scattering, Visualization, Environmental sensing

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Proceedings Article | 2 October 2003 Paper

Functional optical coherence tomography to reveal functional architecture of cat visual cortex in vivo

Ryota Homma, Hirofumi Kadono, Manabu Tanifuji, Rajagopalan Uma Maheswari

Proceedings Volume 5140, (2003) https://doi.org/10.1117/12.500567

KEYWORDS: Optical coherence tomography, Brain, Visual cortex, Brain mapping, Neurons, Imaging systems, Optical imaging, In vivo imaging, Neuroimaging, Visualization

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Proceedings Article | 27 May 2003 Paper

Hilbert transform method for analysis of ESPI for the study of dynamic events

Violeta Madjarova, Hirofumi Kadono, Satoru Toyooka

Proceedings Volume 4933, (2003) https://doi.org/10.1117/12.516631

KEYWORDS: Speckle, Signal processing, CCD cameras, Speckle pattern, Phase shift keying, Filtering (signal processing), Data processing, Spatial resolution, Image processing, Image filtering

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Proceedings Article | 27 May 2003 Paper

Monitoring of the influence of environmental conditions on plant growth using statistical interferometry

Hirofumi Kadono, Tomohiro Nakamura, Kohji Matsui, Satoru Toyooka

Proceedings Volume 4933, (2003) https://doi.org/10.1117/12.516667

KEYWORDS: Speckle, Interferometry, Environmental monitoring, Speckle pattern, Beam splitters, Biomedical optics, Environmental sensing, Temporal resolution, Standards development, Error analysis

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Proceedings Article | 14 June 2002 Paper

Functional imaging of cat primary visual cortex with optical coherence tomography

Uma Rajagopalan, Hideyuki Takaoka, Ryota Homma, Hirofumi Kadono, Manabu Tanifuji

Proceedings Volume 4619, (2002) https://doi.org/10.1117/12.470474

KEYWORDS: Optical coherence tomography, Visual cortex, Functional imaging, Reflectivity, Brain, Scattering, Signal detection, Visualization, Neurons, Mirrors

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Proceedings Article | 19 July 1999 Paper

Optical coherence tomographic imaging system for investigating cortical functional organization of brain: a simulation study

Rajagopalan Maheswari, Hirofumi Kadono, Manabu Tanifuji

Proceedings Volume 3749, (1999) https://doi.org/10.1117/12.354805

KEYWORDS: Optical coherence tomography, Imaging systems, Neuroimaging, Monte Carlo methods, Particles, Tomography, Brain, Coherence (optics), Iron, Reflectivity

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Proceedings Article | 19 July 1999 Paper

Thermal strain measurement of joint materials over a small spatial region using statistical interferometry

Hirofumi Kadono, Hirofumi Kitajima, Satoru Toyooka

Proceedings Volume 3749, (1999) https://doi.org/10.1117/12.354986

KEYWORDS: Speckle, Interferometry, Interfaces, Spatial resolution, Protactinium, Beam splitters, Speckle pattern, Phase shift keying, Computer simulations, Ceramics

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Proceedings Article | 7 May 1999 Paper

Application of an antiferroelectric liquid crystal cell as a self-aligning phase modulator

Hirofumi Kadono, Satoru Toyooka

Proceedings Volume 3740, (1999) https://doi.org/10.1117/12.347822

KEYWORDS: Modulators, Phase shift keying, Liquid crystals, Modulation, Phase modulation, Phase shifting, Interferometers, Molecules, Optical filters, Phase contrast

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Proceedings Article | 29 April 1999 Paper

Generation of contrast-enhanced speckle field and its application to surface roughness measurement

Hirofumi Kadono, Shinji Hoshino, Satoru Toyooka

Proceedings Volume 3729, (1999) https://doi.org/10.1117/12.346809

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Proceedings Article | 20 March 1997 Paper

Phase-shifting speckle interferometer using liquid crystal cell

Hirofumi Kadono, Satoru Toyooka

Proceedings Volume 2921, (1997) https://doi.org/10.1117/12.269830

KEYWORDS: Liquid crystals, Speckle, Phase shift keying, Phase shifting, Modulators, Interferometers, Phase shifts, Digital filtering, Shearing interferometers, Computer simulations

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Proceedings Article | 1 September 1996 Paper

Measurement of thermal expansion by statistical interferometry

H. Kadono

Proceedings Volume 2778, 2778FJ (1996) https://doi.org/10.1117/12.2316248

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Proceedings Article | 1 December 1991 Paper

Liquid-crystal phase modulator used in DSPI

Hirofumi Kadono, Satoru Toyooka

Proceedings Volume 1554, (1991) https://doi.org/10.1117/12.49506

KEYWORDS: Liquid crystals, Speckle, Phase shift keying, Modulators, Phase modulation, Phase shifts, Ferroelectric materials, Phase shifting, Modulation, Shearing interferometers

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Proceedings Article | 1 December 1991 Paper

Statistical interferometry based on the statistics of speckle phase

Hirofumi Kadono, Satoru Toyooka

Proceedings Volume 1554, (1991) https://doi.org/10.1117/12.49518

KEYWORDS: Speckle, Phase shifts, Interferometry, Optical interferometry, Birefringence, Solids, Mechanics, Phase interferometry, Error analysis, Optical components

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