Research on the formation criterion of supported bilayer lipid membranes for biosensors development

Shengping Liu; Yunlong Wei; Guoming Chen

doi:10.1117/12.664233

21 March 2006 Research on the formation criterion of supported bilayer lipid membranes for biosensors development

Shengping Liu, Yunlong Wei, Guoming Chen

Proceedings Volume 6040, ICMIT 2005: Mechatronics, MEMS, and Smart Materials; 60401R (2006) https://doi.org/10.1117/12.664233
Event: ICMIT 2005: Merchatronics, MEMS, and Smart Materials, 2005, Chongqing, China

Abstract

Supported Bilayer Lipid Membrane (s-BLM) is a kind of mimicking biomembrane in vitro. The s-BLM was widely applied as a cell membrane model and sensing material of biosensors and biomolecular devices. An electrode based on s-BLM modified with valinomycin was fabricated. Utilizing Cyclic Voltammetry (CV), the influence of temperature on the formation of s-BLM on the top section of the electrode was investigated. The results show that the BLM formed on the top of stainless electrode occurs "phase transition" around 39 Celsius degree. This alters the CV characteristics of BLM. The "phase transition temperature" can be as a new judgment method of the s-BLM configuration.

Citation Download Citation

Shengping Liu, Yunlong Wei, and Guoming Chen "Research on the formation criterion of supported bilayer lipid membranes for biosensors development", Proc. SPIE 6040, ICMIT 2005: Mechatronics, MEMS, and Smart Materials, 60401R (21 March 2006); https://doi.org/10.1117/12.664233

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