In gastrointestinal endoscopic surgery, bleeding from the accidental resection of hidden vessels is a major complication, requiring immediate conversion to open surgery. Methods of visualizing occult vessels have been proposed using the FDA approved fluorescent dye Indocyanine green (ICG), but Native label-free fluorescence of the submucosa—present up till about 886 nm—prevents the use ICG in near-infrared (NIR) window I (700 nm to 900 nm). Instead, absorption imaging is preferred; the darker vessels are visible to 4.5 mm deep. Using data from Raman scattering, absorption, native fluorescence, SHG and the photon excitation fluorescence we investigate the spectral properties and propose optimal parameters for differentiation of blood vessels from surrounding tissue in a variety of tissue types in NIR window II (1000 nm to 1350 nm) and NIR window III (1550 nm to 1900 nm, the “Golden Window”) as a complement to absorption imaging.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.