We propose a highly efficient Surface Plasmon Resonance (SPR)-based sensing device to detect various anaemic conditions in human blood. A thin aluminum (Al) metal-coated glass prism is used to excite surface plasmons. A high-dielectric constant material, TiO2, is used over Al-metal to enhance the sensitivity, and a layer of fluorinated graphene (FG) is used as a bio-recognition element to study biomolecular interactions. To demonstrate sensing application, an Al (30 nm)-based engineered plasmonic device with an optimized value of TiO2 (2nm) and functionalized with an FG layer is utilized to detect various hemoglobin (Hb) concentrations in human blood at a wavelength of 1550 nm. A value of sensitivity of 123 °/RIU and FOM 439 RIU-1 is observed for the proposed Al-TiO2-FG-based SPR sensor. The proposed sensing device can be used as a biosensor to detect anemia by accurately evaluating the level of Hb concentration, making it the best candidate for biomedical applications.
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