Dr. Muhammad Junaid Amin Profile

Dr. Muhammad Junaid Amin

at Princeton Univ

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Publications (7)

Proceedings Article | 5 March 2021 Presentation + Paper

Intensity uniformity optimization in spatial-light-modulator-based multifocal microscope

M. Junaid Amin, Sabine Petry, Haw Yang, Joshua Shaevitz

Proceedings Volume 11649, 116490P (2021) https://doi.org/10.1117/12.2578859

KEYWORDS: Spatial light modulators, Microscopes, Multiphoton fluorescence microscopy, Modulators, Diffraction gratings, Algorithm development, Stereoscopy, Sensors, Optimization (mathematics), Microscopy

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Proceedings Article | 21 August 2020 Presentation + Paper

Three-dimensional super line-localization in low signal-to-noise microscope images via prior-apprised unsupervised learning (PAUL)

Shuhui Yin, M. Junaid Amin, Nyssa Emerson, Haw Yang

Proceedings Volume 11510, 115101L (2020) https://doi.org/10.1117/12.2567752

KEYWORDS: 3D image processing, Microscopes, Signal to noise ratio, Point spread functions, Principal component analysis, Feature extraction

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Biological processes such as processive enzyme turnover and intracellular cargo trafficking involve the dynamic motion of a small ”article" along a curvilinear biopolymer track. To understand these processes that occur across multiple length and time scales, one must acquire both the trajectory of the particle and the position of the track along which it moves, possibly by combining high-resolution single-particle tracking with conventional microscopy. Yet, usually there is a significant resolution mismatch between these modalities: while the tracked particle is localized with a precision of 10 nm, the image of the surroundings is limited by optical diffraction, with 200 nm lateral and 500 nm axial resolutions. Compared to the particle's trajectory, the surrounding curvilinear structure appears as a blurred and noisy image. This disparity in the spatial resolutions of the particle trajectory and the surrounding curvilinear structure image makes data reconstruction, as well as interpretation, particularly challenging. Analysis is further complicated when the curvilinear structures are oriented arbitrarily in 3D space. Here, we present a prior-apprised unsupervised learning (PAUL) approach to extract information from 3D images where the underlying features resemble a curved line such as a filament or microtubule. This three-stage framework starts with a Hessian-based feature enhancement, which is followed by feature registration, where local line segments are detected on repetitively sampled subimage tiles. In the final stage, statistical learning, segments are clustered based on their geometric relationships. Principal curves are then approximated from each segment group via statistical tools including principal component analysis, bootstrap and kernel transformation. This procedure is characterized on simulated images, where sub-voxel medium deviations from true curves have been achieved. The 3D PAUL approach has also been implemented for successful line localization in experimental 3D images of gold nanowires obtained using a multifocal microscope. This work not only bridges the resolution gap between two microscopy modalities, but also allows us to conduct 3D super line-localization imaging experiments, without using super-resolution techniques.

Proceedings Article | 29 April 2016 Paper

Agile wavefront splitting interferometry and imaging using a digital micromirror device

Juan Pablo La Torre, M. Junaid Amin, Nabeel Riza

Proceedings Volume 9896, 98960B (2016) https://doi.org/10.1117/12.2228373

KEYWORDS: Wavefronts, Digital micromirror devices, Interferometers, Spatial light modulators, Interferometry, Sensors, Digital imaging, Imaging systems, Beam splitters, Staring arrays, Wavefronts, Spatial light modulators, 3D image processing, Cameras, Micromirrors, Double patterning technology

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Proceedings Article | 29 April 2016 Paper

Motionless active depth from defocus system using smart optics for camera autofocus applications

M. Junaid Amin, Nabeel Riza

Proceedings Volume 9896, 98960N (2016) https://doi.org/10.1117/12.2227753

KEYWORDS: Cameras, Imaging systems, Computing systems, Active optics, Sensors, Light sources, Laser beam propagation, Apertures, Optical sensing, Three dimensional sensing, Imaging systems, Projection systems, Distance measurement, Image processing, Optical sensors, Spatial frequencies, Fourier transforms

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Proceedings Article | 15 May 2014 Paper

Smart imaging using laser targeting: a multiple barcodes application

M. Junaid Amin, Nabeel Riza

Proceedings Volume 9141, 91411H (2014) https://doi.org/10.1117/12.2047596

KEYWORDS: Imaging systems, Detection and tracking algorithms, Detector arrays, Receivers, Iron, Transmitters, Sensors, Target detection, Inspection, Charge-coupled devices

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Proceedings Article | 6 March 2014 Paper

Smart optical writing head design for laser-based manufacturing

M. Junaid Amin, Nabeel Riza

Proceedings Volume 8967, 89671D (2014) https://doi.org/10.1117/12.2038352

KEYWORDS: Head, Optics manufacturing, Optical design, Iron, Laser cutting, Laser applications, Laser development, Control systems, Geometrical optics, Laser manufacturing

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Proceedings Article | 28 February 2014 Paper

Eye vision system using programmable micro-optics and micro-electronics

Nabeel Riza, M. Junaid Amin, Mehdi Riza

Proceedings Volume 8930, 89300C (2014) https://doi.org/10.1117/12.2038334

KEYWORDS: Eye, Eyewear, Micro optics, Control systems, Wireless communications, Energy harvesting, Imaging systems, Microelectronics, Liquid crystals, Eye models

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Showing 5 of 7 publications

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