In order to safely and effectively treat patients with methylene blue photodynamic therapy (MB-PDT) for sterilization of deep tissue abscesses, abscess optical properties must be determined. We demonstrate the ability of our compact optical probe along with a Monte Carlo-based lookup table to retrieve optical properties in tissue simulating phantoms containing Intralipid as a scatterer, and Methylene Blue (MB) and/or Mn(III) meso-Tetra (4-sulfonatophenyl) porphine (MnTPPS) as absorbers. Our results demonstrate the system’s ability to accurately recover optical properties in the presence of multiple absorbers. Future applications for this system will allow for patient specific treatment throughout ongoing clinical trials.
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