Near-infrared light can be used to determine the optical properties (absorption and scattering) of human tissue. Optical tomography uses this principle to image the internal structure of parts of the body by measuring the light that is scattered in the tissue. An imager for optical tomography was designed based on a detector with 128x128 single photon pixels that included a bank of 32 time-to-digital converters. Due to the high spatial resolution and the possibility of performing time resolved measurements, a new contactless setup has been conceived. The setup has a resolution of 97ps and operates with a laser source with an average power of 3mW. This new setup generated an high amount of data that could not be processed by established methods, therefore new concepts and algorithms were developed to take advantage of it. Simulations show that the potential resolution of the new setup would be much higher than previous designs. Measurements have been performed showing its potential. Images derived from the measurements showed that it is possible to reach a resolution of at least 5mm.
An imager for optical tomography was designed based on a detector with 128×128 single-photon pixels that
included a bank of 32 time-to-digital converters. Due to the high spatial resolution and the possibility of
performing time resolved measurements, a new contact-less setup has been conceived in which scanning of the
object is not necessary. This enables one to perform high-resolution optical tomography with much higher
acquisition rate, which is fundamental in clinical applications. The setup has a resolution of 97ps and operates
with a laser source with an average power of 3mW. This new imaging system generated a high amount of data
that could not be processed by established methods, therefore new concepts and algorithms were developed to
take full advantage of it. Images were generated using a new reconstruction algorithm that combined general
inverse problem methods with Fourier transforms in order to reduce the complexity of the problem. Simulations
show that the potential resolution of the new setup is in the order of millimeters. Experiments have been
performed to confirm this potential. Images derived from the measurements demonstrate that we have already
reached a resolution of 5mm.
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