Dr. Alla B. Bucharskaya Profile

Dr. Alla B. Bucharskaya

Head of Depatrment at Saratov State Medical Univ

SPIE Involvement:

Author

Publications (37)

Proceedings Article | 29 April 2022 Paper

Morphological changes in rat lung tissue during inhalation of e-cigarette liquid aerosol

Alla Bucharskaya, Dmitry Mudrak, Irina Yanina, Nikita Navolokin, Alexandr Polozhenkov, Elina Genina, Yury Kistenev, Valery Tuchin

Proceedings Volume 12192, 1219210 (2022) https://doi.org/10.1117/12.2627915

KEYWORDS: Lung, Tissues, Liquids, Tissue optics, In vivo imaging, Optical coherence tomography, Scattering, Aerosols, Light scattering, Absorption

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Proceedings Article | 29 April 2022 Paper

The novel photosensitizer galactose: lutetium (Lu)-phthalocyanine for photodynamic therapy in tumor-bearing mice

Alla Bucharskaya, Galina Maslyakova, Nikita Navolokin, Georgy Terentyuk, Vanya Mantareva, Vadim Genin, Elina Genina, Valery Tuchin

Proceedings Volume 12192, 121920Z (2022) https://doi.org/10.1117/12.2627759

KEYWORDS: Photodynamic therapy, Tumors, Lutetium, Tissues, Medical research, Cell death, Skin, Photomicroscopy, Laser sources, Inflammation

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Proceedings Article | 4 May 2021 Paper

The assessment of tumor vascularization degree for predicting the effectiveness of plasmonic photothermal and photodynamic therapy

Alla Bucharskaya, Galina Maslyakova, Marina Chekhonatskaya, Svetlana Pakhomy, Dmitry Mudrak, Nikita Navolokin, Georgy Terentyuk, Ekaterina Borisova, Vanya Mantareva, Ivan Angelov, Boris Khlebtsov, Nikolai Khlebtsov, Vadim Genin, Alexey Bashkatov, Elina Genina, Valery Tuchin

Proceedings Volume 11845, 1184508 (2021) https://doi.org/10.1117/12.2590411

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Proceedings Article | 4 May 2021 Paper

LASCA monitoring of dose-dependent dynamics of tumor growth under the influence of Chlamydia psittaci AMK-16 specific ornithosis antigen

Anna Lyapina, Maxim Lavrukhin, Larisa Padilo, Maria Khizhnyakova, Nadejda Filonova, Onega Ulianova, Galina Maslyakova, Alla Bucharskaya, Nikita Navolokin, Sergey Dobdin, Anatoly Skripal, Vitaliy Evstifeev, Olga Larionova, Sergey Ulyanov, Valentina Feodorova

Proceedings Volume 11845, 118450E (2021) https://doi.org/10.1117/12.2588596

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Proceedings Article | 4 May 2021 Paper

Optical properties of model cholangiocarcinoma tissues in the spectral range of 350-2250 nm in laser photothermolysis treatment

Vadim Genin, Alla Bucharskaya, Elina Genina, Georgy Terentyuk, Nikolai Khlebtsov, Valery Tuchin, Alexey Bashkatov

Proceedings Volume 11845, 118450Z (2021) https://doi.org/10.1117/12.2590422

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Proceedings Article | 9 April 2020 Paper

Speckle-contrast imaging of pathological tissue microhemodynamics in the development of various diabetes models

Polina Dyachenko (Timoshina), Denis Alexandrov, Alla Bucharskaya, Valery Tuchin

Proceedings Volume 11457, 114570K (2020) https://doi.org/10.1117/12.2564100

KEYWORDS: Blood circulation, Blood, Animal model studies, Pancreas, Laser speckle contrast imaging, Speckle imaging, Speckle, Optical clearing, Tissues, Glucose

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Proceedings Article | 9 April 2020 Paper

Functional and morphological changes in the testicular tissue of rat newborns during chronic hypoxia: experimental study

T. Palatova, G. Maslyakova, A. Bucharskaya, E. Genina, A. Bashkatov

Proceedings Volume 11457, 114570N (2020) https://doi.org/10.1117/12.2563415

KEYWORDS: Hypoxia, Tissues, Testis, Oxygen, Reflectivity, Biomedical optics, Animal model studies, Tissue optics

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Proceedings Article | 9 April 2020 Paper

Pilot study of glycerol diffusion in ex vivo skin: a comparison of alloxan and streptozotocin diabetes models

Daria Tuchina, Alla Bucharskaya, Valery Tuchin

Proceedings Volume 11457, 114570J (2020) https://doi.org/10.1117/12.2563794

KEYWORDS: Skin, Diffusion, Transmittance, Collimation, Optical clearing, Tissues, Tissue optics, Refractive index, Animal model studies, Glucose

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Proceedings Article | 9 April 2020 Paper

Can the infection, caused by Chlamydia psittaci, produce the stimulation of the growth of a malignant tumor: studying by using t-LASCA technique on animal model

Larisa Padilo, Onega Ulianova, Galina Maslyakova, Alla Bucharskaya, Sergey Dobdin, Irina Subbotina, Anatoly Skripal, Yaroslav Drevko, Vitaly Evstifeev, Olga Larionova, Sergey Ulyanov, Valentina Feodorova

Proceedings Volume 11457, 114570I (2020) https://doi.org/10.1117/12.2563841

KEYWORDS: Tumors, Animal model studies, Tumor growth modeling, Solids, Speckle, Skin, Cameras, Error analysis, Diagnostics, Cancer

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Proceedings Article | 8 April 2020 Presentation

Study tissue microhemodynamics in area of tumor at optical clearing by speckle-contrast imaging (Conference Presentation)

Polina Dyachenko Timoshina, Alla Bucharskaya, Valery Tuchin, Aleksandr Shkurinov

Proceedings Volume 11363, 113631Q (2020) https://doi.org/10.1117/12.2554992

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The results of an experimental study of changes in the microcirculation of subcutaneous blood flow in a malignant tumor using laser speckle contrast imaging (LSCI) using an optical clearing agent of 70% glycerol solution are presented. In this study, for hemodynamic monitoring we used the speckle contrast method, which is one of the laser speckle imaging methods. This method is based on calculation of contrast of time-averaged dynamic speckles in dependence on the exposure time at the registration of the speckle-modulated images. Analysis of change of hemodynamic was carried out depending on the stage of development of pathologyIn research, we used 15 white laboratory rats Wistar weighing 300-500 g. A tumor was inoculated in laboratory rats by subcutaneous injection of 0.5 ml of a 25% tumor suspension into the area of the shoulder blades in a Hanks solution strain of PC1 alveolar liver cancer. Laboratory animals were divided into three groups, the first included healthy animals, the second - animals with an inoculated tumor 14 days after injection and the third - animals with an inoculated tumor 28 days after injection. It was found that the blood flow rate in pathological group No. 2 was reduced by 25% relative to control measurements of group No. 1, in pathological group No. 3 increased by 20% relative to control measurements. Also, the results showed that the use of a 70% glycerol solution reduced the blood flow velocity in the control group by about 2 times. Moreover, in pathological groups, the effect of the solution on the blood flow is more pronounced, in the group, the measurements on which were carried out 14 days after the inoculation of the tumor, the blood flow rate decreased by 2.8 times, after 28 days - by 4 times. The results obtained in the study of disorders of the microcirculation of the subcutaneous blood flow under the conditions of the development of a malignant tumor show that the development of diseases in animals causes changes in the microcirculatory system, and the use of optical clearing agents demonstrates changes in vascular permeability under conditions of the development of pathologies.

Proceedings Article | 8 April 2020 Presentation

THz properties of rat skin and extracts at exposure to hyperosmotic solutions (Conference Presentation)

Ekaterina Lazareva, Maxim Nazarov, Alla Bucharskaya, Valery Tuchin, Alexander Shkurinov

Proceedings Volume 11363, 1136328 (2020) https://doi.org/10.1117/12.2560376

KEYWORDS: Tissue optics, Skin, Terahertz radiation, Optical clearing, Tumors, Scattering, Absorption, Imaging spectroscopy, Glucose, Water

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Application of many optical methods, such as photoacoustics, optical coherent tomography, and terahertz spectroscopy, for tissue imaging and disease diagnostics is limited due to small probing depth caused by strong scattering and absorption in tissues [1, 2]. It is possible to increase the efficiency of optical techniques by using tissue optical clearing (TOC), which allows one to control tissue optical properties by exposing tissue to biocompatible liquids - optical clearing agents (OCAs). When exposed to an OCA with hyperosmotic properties, such as glycerol or highly concentrated glucose solution, it is possible to achieve a considerable decrease of tissue scattering within the entire spectral range and absorption on the water bands due to refractive index matching phenomenon and dehydration of the tissue, and therefore to get a significant increase of the optical and THz wave transmittance [1-3]. In vitro studies were performed on laboratory rats of the Vistar strain (sexually mature females weighing 300–400 g were used). The animals were inoculated with the tumor cells by subcutaneous injection into the area of the scapulae. Studies were conducted in 28 days after injection. The weight and thickness of the samples were measured before and after optical clearing by using a micrometer with an accuracy of ±0.001 mm and an analytical balance (Scientech, SA210, USA) with an accuracy of ±1 mg. The samples of the area 1.5*1.5 cm2 were placed in a closed sealed container, to which was added 2 ml of OCA. 70% glycerol solution, 40% glucose solution and 50% fructose in a 30% alcohol solution were used with the addition of saline as an OCA. The transmission spectrum of glycerol in the frequency range of 0.05–1.0 THz was measured by using the terahertz (THz) time-domain spectrometer. Measurements of the refractive index of OCA were carried out before the start of the experiment and every 5 minutes after placing the skin sample in the solution with OCA for 15 minutes, then every 10 minutes for another 45 minutes. It was found that the effectiveness of optical clearing of the skin over the tumor is higher compared to healthy skin. A good correlation was shown between the kinetics of the sample mass and THz absorption and refraction. An assessment of skin dehydration also showed that the concentration of water extracted from the skin above the tumor is greater compared to healthy. It is especially important that enhancing the image contrast due to dehydration and TOC in the pathology area is extremely significant in diagnosing precancerous conditions and treating early stages of tumor, due to the possibility of selective increase of the scattering contrast of cell nuclei relative to surrounding cytoplasm and interstitial fluid and thus following their size and internal rearrangements [5].

Proceedings Article | 2 April 2020 Presentation

Photodynamic treatment of cholangiocarcinoma with phthalocyanine compounds in laboratory animals (Conference Presentation)

Ekaterina Borisova, Alla Bucharskaya, Nikita Navolokin, Vadim Genin, Elina Genina, Alexey Bashkatov, Vanya Mantareva, Ivan Angelov

Proceedings Volume 11363, 1136325 (2020) https://doi.org/10.1117/12.2555952

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The new generations of photoactive compounds, which are derivatives of already well-established groups of photosensitizers, together with the modern light sources in the spectral region of their activation and in the PDT window range, are emerging as a reliable phototherapy approach for tumour treatment with higher efficiency. The substitution of a highly hydrophobic phthalocyanine with galactose units could improve the solubility and to decrease significant aggregation in polar solvents. The control group of rats with transplanted cholangiocarcinoma without any treatment was used for comparison of PDT effectiveness. In the second group the white outbred male rats with cholangiocarcinoma lesions were treated using Zn-phthalocyanine, as a typical representative of phthalocyanine photosensitizers with known photodynamic properties and the third group of animals was treated with galactose – Lu-phthalocyanine, as a novel derivative from the same family with two specific differences – presence of galactose and replacing of Zn(II) with Lu(III) ion. To compare the PDT effectiveness of both compounds the same drug doses were applied - 2 mg/kg, applied by intratumoural injection. Diode laser source at 670 nm, on 50 mW output power with power density applied 200 mW/cm2 was applied for 1000 sec to obtain total irradiation dose of 200 J/cm2 for each lesion. 3 days after treatment, the animals were withdrawn from the experiment. Tissue from the central zone and periphery of the tumor was taken for morphological examination and fixed in 10% formalin. Serial paraffin sections were stained with hematoxilin-eosin and by immunohistochemical staining with antibodies to proliferation marker Ki-67 and apoptosis marker BAX. After photodynamic therapy, pronounced necrobiotic changes in combination with an inflammatory reaction were developed at the central zone of tumors. The dystrophic changes, reduction of proliferation and development of apoptosis in tumor cells were observed on tumor periphery as well.

Proceedings Article | 3 June 2019 Paper

Functional and morphological changes in the mother-placenta-fetus system during chronic hypoxia (experimental study)

Tatyana Palatova, Galina Maslyakova, Marina Chekhonatskaya, Alla Bucharskaya, Elina Genina, Alexey Bashkatov

Proceedings Volume 11065, 110651W (2019) https://doi.org/10.1117/12.2523634

KEYWORDS: Hypoxia, Blood circulation, Tissues, Liver, Heart, Kidney, Ultrasonography, Resistance, Fetus, Reflectivity

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Proceedings Article | 1 March 2019 Paper

Exogenous agent diffusivity in tissues as a biomarker of diabetes mellitus pathology

Daria Tuchina, Alexey Bashkatov, Alla Bucharskaya, Valery Tuchin

Proceedings Volume 10877, 108770X (2019) https://doi.org/10.1117/12.2506644

KEYWORDS: Skin, Tissues, Optical clearing, In vivo imaging, Transmittance, Collimation, Optical coherence tomography, Pathology, Signal attenuation, Diagnostics

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Proceedings Article | 1 March 2019 Paper

Speckle-contrast imaging of pathological tissue microhemodynamics at optical clearing

Polina Timoshina, Alla Bucharskaya, Nikita Navolokin, Valery Tuchin

Proceedings Volume 10877, 108770Z (2019) https://doi.org/10.1117/12.2508794

KEYWORDS: Blood circulation, Blood, Laser speckle contrast imaging, Optical clearing, Speckle, Pancreas, Tissue optics, Speckle imaging, Animal model studies, Tissues

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Proceedings Article | 26 April 2018 Paper

Reduction of intoxication in the rats with transplanted tumors under the influence of Gratiola officinalis L. extract

N. Navolokin, A. Polukonova, I. Plastun, D. Mudrak, A. Bokarev, G. Afanasyeva, A. Bucharskaya, G. Maslyakova, N. Polukonova

Proceedings Volume 10716, 107160U (2018) https://doi.org/10.1117/12.2315342

KEYWORDS: Tumors, Hydrogen, Blood, Molecules, Numerical simulations, Bridges, Liver cancer, Numerical modeling, Cancer, Molecular interactions

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Proceedings Article | 26 April 2018 Paper

Investigation of change of tumor optical properties after laser-induced plasmon-resonant photothermal treatment of transplanted tumors in rats

Vadim Genin, Elina Genina, Alla Bucharskaya, Valery Tuchin, Nikolay Khlebtsov, Georgy Terentyuk, Alexey Bashkatov

Proceedings Volume 10716, 107160Z (2018) https://doi.org/10.1117/12.2315213

KEYWORDS: Tumors, Tissues, Scattering, Laser scattering, Nanoparticles, Absorption, Skin, Optical properties, Gold, Cancer

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Proceedings Article | 19 February 2018 Paper

The interaction between the meningeal lymphatics and blood-brain barrier

O. Semyachkina-Glushkovskaya, A. Abdurashitov, A. Dubrovsky, A. Pavlov, N. Shushunova, G. Maslyakova, N. Navolokin, A. Bucharskaya, V. Tuchin, J. Kurths

Proceedings Volume 10495, 104950J (2018) https://doi.org/10.1117/12.2289406

KEYWORDS: Lymphatic system, Blood brain barrier, Brain, Optical coherence tomography, Photodynamic therapy, Visualization, Tissues, Tomography, Blood

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Proceedings Article | 19 February 2018 Paper

The inflammation markers in serum of tumor-bearing rats after plasmonic photothermal therapy

Alla Bucharskaya, Galina Maslyakova, Georgy Terentyuk, Galina Afanasyeva, Nikita Navolokin, Natalia Zakharova, Boris Khlebtsov, Nikolai Khlebtsov, Alexey Bashkatov, Elina Genina, Valery Tuchin

Proceedings Volume 10495, 104950X (2018) https://doi.org/10.1117/12.2289369

KEYWORDS: Tumors, Gold, Nanorods, Nanoparticles, Laser therapeutics, Plasmonics, Laser irradiation, Tissues, Liver cancer, Inflammation

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SPIE Journal Paper | 5 February 2018 Open Access

Delivery and reveal of localization of upconversion luminescent microparticles and quantum dots in the skin in vivo by fractional laser microablation, multimodal imaging, and optical clearing

Elena Volkova, Irina Yu. Yanina, Elina Genina, Alexey Bashkatov, Julia Konyukhova, Alexey Popov, Elena Speranskaya, Alla Bucharskaya, Nikita Navolokin, Irina Yu. Goryacheva, Vyacheslav Kochubey, Gleb Sukhorukov, Igor Meglinski, Valery Tuchin

JBO, Vol. 23, Issue 02, 026001, (February 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.2.026001

KEYWORDS: Skin, Particles, Upconversion, In vivo imaging, Tissues, Optical clearing, Nanoparticles, Optical coherence tomography, Luminescence, Quantum dots

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SPIE Journal Paper | 23 December 2017 Open Access

Application of optical coherence tomography for in vivo monitoring of the meningeal lymphatic vessels during opening of blood–brain barrier: mechanisms of brain clearing

Oxana Semyachkina-Glushkovskaya, Arkady Abdurashitov, Alexander Dubrovsky, Denis Bragin, Olga Bragina, Natalia Shushunova, Galina Maslyakova, Nikita Navolokin, Alla Bucharskaya, Valery Tuchind, Jürgen Kurths, Alexander Shirokov

JBO, Vol. 22, Issue 12, 121719, (December 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.12.121719

KEYWORDS: Lymphatic system, Blood brain barrier, Brain, Optical coherence tomography, Tissues, Confocal microscopy, Visualization, Imaging systems, Luminescence, Neuroimaging

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SPIE Journal Paper | 25 May 2017 Open Access

Morphology alterations of skin and subcutaneous fat at NIR laser irradiation combined with delivery of encapsulated indocyanine green

Irina Yu. Yanina, Nikita A. Navolokin, Yulia Svenskaya, Alla Bucharskaya, Galina Maslyakova, Dmitry Gorin, Gleb Sukhorukov, Valery Tuchin

JBO, Vol. 22, Issue 05, 055008, (May 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.5.055008

KEYWORDS: Laser irradiation, Indocyanine green, Near infrared, Skin, Laser therapeutics, In vivo imaging, Laser tissue interaction, Semiconductor lasers

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Proceedings Article | 24 March 2017 Paper

The assesment of effectiveness of plasmonic resonance photothermal therapy in tumor-bearing rats after multiple intravenous administration of gold nanorods

Alla Bucharskaya, Galina Maslyakova, Nikita Navolokin, Georgy Terentyuk, Boris Khlebtsov, Nikolai Khlebtsov, Alexey Bashkatov, Elina Genina, V. Tuchin

Proceedings Volume 10336, 103360Q (2017) https://doi.org/10.1117/12.2268293

KEYWORDS: Nanorods, Plasmonics, Gold, Tumors, Tissues, Laser therapeutics, Nanoparticles, Liver cancer, Absorption, Semiconductor lasers

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Proceedings Article | 24 March 2017 Paper

Investigation of flavonoid influence on peroxidation processes intensity in the blood

N. Navolokin, D. Mudrak, I. Plastun, A. Bucharskaya, K. Agandeeva, A. Ivlichev, S. Tychina, G. Afanasyeva, N. Polukonova, G. Maslyakova

Proceedings Volume 10336, 103360X (2017) https://doi.org/10.1117/12.2268336

KEYWORDS: Tumors, Hydrogen, Blood, Liver cancer, Molecules, Numerical simulations, Molecular interactions, Numerical modeling, Cancer, Animal model studies

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Proceedings Article | 20 February 2017 Paper

The effects of prolonged oral administration of gold nanoparticles on the morphology of hematopoietic and lymphoid organs

Alla Bucharskaya, Svetlana Pakhomy, Olga Zlobina, Galina Maslyakova, Nikita Navolokin, Olga Matveeva, Boris Khlebtsov, Vladimir Bogatyrev, Nikolai Khlebtsov, Valery Tuchin

Proceedings Volume 10065, 100650V (2017) https://doi.org/10.1117/12.2252534

KEYWORDS: Nanoparticles, Gold, Lymphatic system, Tissues, Spleen, Bone, Plasmonics, In vivo imaging, Blood, Particles, Biomedical optics, Medical research

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Proceedings Article | 21 April 2016 Paper

Nanoparticles and nanostructured carriers for drug delivery and contrast enhancement

Olga Godage, Alla Bucharskaya, Nikita Navolokin, Sergey German, Viktor Zuev, Georgy Terentyuk, Galina Maslyakova, Dmitry Gorin

Proceedings Volume 9917, 99171H (2016) https://doi.org/10.1117/12.2229872

KEYWORDS: Nanoparticles, Magnetism, Magnetic resonance imaging, Tumors, Tissues, Iron, Nanostructuring, Oxides, Nanotechnology, Particles

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Proceedings Article | 21 April 2016 Paper

The morphological changes in transplanted tumors in rats at plasmonic photothermal therapy

Alla Bucharskaya, Galina Maslyakova, Nikita Navolokin, Nataliya Dikht, Georgy Terentyuk, Alexey Bashkatov, Elina Genina, Boris Khlebtsov, Nikolai Khlebtsov, Valery Tuchin

Proceedings Volume 9917, 991708 (2016) https://doi.org/10.1117/12.2229873

KEYWORDS: Nanorods, Plasmonics, Gold, Oncology, Tumors, Nanoparticles, Liver cancer, Cell death, Tissues, Biomedical optics

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Proceedings Article | 21 April 2016 Paper

Comparison of membrane-protective activity of antioxidants quercetine and Gratiola Officinalis L. extract under conditions of photodynamic haemolysis

N. Tkachenko, E. Bykova, A. Pravdin, N. Navolokin, N. Polukonova, A. Bucharskaya, D. Mudrak, A. Prilepskii

Proceedings Volume 9917, 99170L (2016) https://doi.org/10.1117/12.2228291

KEYWORDS: Oxygen, Absorbance, Ions, Cervical cancer, Statistical modeling, Chemical analysis, In vitro testing, Image analysis, Error analysis, Magnesium

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Proceedings Article | 9 March 2016 Paper

The morphological changes in lymphoid organs and peripheral blood indicators in rats after peroral administration of gold nanoparticles

A. Bucharskaya, S. Pakhomy, O. Zlobina, G. Maslyakova, O. Matveeva, I. Bugaeva, N. Navolokin, B. Khlebtsov, V. Bogatyrev, N. Khlebtsov, V. Tuchin

Proceedings Volume 9709, 97090V (2016) https://doi.org/10.1117/12.2216045

KEYWORDS: Gold, Nanoparticles, Blood, Lymphatic system, Bone, Laser therapeutics, Cancer, Oncology, In vitro testing, In vivo imaging, Spleen, Particles, Toxicity, Medical research, Safety

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Proceedings Article | 15 July 2015 Paper

Histological study of subcutaneous fat at NIR laser treatment of the rat skin in vivo

I. Yanina, Yu. Svenskaya, N. Navolokin, O. Matveeva, A. Bucharskaya, G. Maslyakova, D. Gorin, G. Sukhorukov, V. Tuchin

Proceedings Volume 9542, 954216 (2015) https://doi.org/10.1117/12.2183722

KEYWORDS: Laser tissue interaction, Tissues, Skin, Tissue optics, Near infrared, In vivo imaging, Laser irradiation, Laser therapeutics, Cell death, Semiconductor lasers

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Proceedings Article | 15 July 2015 Paper

Luminescence monitoring of particle delivery into rat skin in vivo

E. Volkova, I. Yanina, E. Genina, L. Dolotov, A. Bashkatov, V. Genin, J. Konyukhova, A. Popov, M. Kozintseva, E. Speranskaya, M. Lomova, G. Terentyuk, A. Bucharskaya, N. Navolokin, I. Goryacheva, V. Kochubey, D. Gorin, V. Tuchin, G. Sukhorukov

Proceedings Volume 9537, 95371P (2015) https://doi.org/10.1117/12.2183718

KEYWORDS: Skin, Luminescence, Nanoparticles, Tissues, Particles, Upconversion, In vivo imaging, Optical coherence tomography, Confocal microscopy, Tissue optics

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Proceedings Article | 19 March 2015 Paper

The study of indicators of bone marrow and peripheral blood of rats with diabetes and transplanted liver tumor after intravenous injection of gold nanorods

Nataliya Dikht, Alla Bucharskaya, Galina Maslyakova, Georgy Terentyuk, Olga Matveeva, Nikita Navolokin, Boris Khlebtsov, Nikolai Khlebtsov

Proceedings Volume 9448, 94480U (2015) https://doi.org/10.1117/12.2179757

KEYWORDS: Tumors, Gold, Blood, Bone, Nanoparticles, Liver, Transplantation, Pathology, Cancer, Nanorods

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Proceedings Article | 30 January 2014 Paper

Evaluation of lipid peroxidation activity at intravenous administration of gold nanorods in rats with simulated diabetes and transplanted liver cancer

Alla Bucharskaya, Natalia Dikht, Galina Afanasyeva, Georgy Terentyuk, Galina Maslyakova, Nadezhda Zaraeva, Nikolai Khlebtsov, Boris Khlebtsov

Proceedings Volume 9031, 90310O (2014) https://doi.org/10.1117/12.2048988

KEYWORDS: Gold, Nanoparticles, Liver cancer, Molecules, Blood, Tumors, Nanotechnology, Absorbance, Nanorods, Oxidation

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Proceedings Article | 30 January 2014 Paper

The reversibility of morphological changes in the mesenteric lymph nodes after peroral administration of gold nanoparticles

Olga Zlobina, Svetlana Pakhomy, Alla Bucharskaya, Irina Bugaeva, Galina Maslyakova, Nikolai Khlebtsov, Boris Khlebtsov, Vladimir Bogatyrev

Proceedings Volume 9031, 90310P (2014) https://doi.org/10.1117/12.2048990

KEYWORDS: Lymphatic system, Nanoparticles, Gold, Brain, Particles, Plasma, Biochemistry, Nanomaterials, Tissues, Medicine

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SPIE Journal Paper | 7 May 2012 Open Access

Fat tissue histological study at indocyanine green-mediated photothermal/photodynamic treatment of the skin in vivo

Irina Yanina, Valery Tuchin, Nikita Navolokin, Olga Matveeva, Alla Bucharskaya, Galina Maslyakova, Gregory Altshuler

JBO, Vol. 17, Issue 5, 058002, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.5.058002

KEYWORDS: Laser tissue interaction, Skin, Tissues, Tissue optics, In vivo imaging, Laser irradiation, Magnesium, Absorption, Statistical analysis, Near infrared

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Proceedings Article | 29 February 2012 Paper

Studies of lipid peroxidation of rat blood after in vivo photodynamic treatment

Irina Yu. Yanina, Nikita Navolokin, Victoria Nikitina, Alla Bucharskaya, Galina Maslyakova, Valery Tuchin

Proceedings Volume 8337, 83370G (2012) https://doi.org/10.1117/12.923779

KEYWORDS: Blood, Photodynamic therapy, In vivo imaging, Calibration, Tissues, Proteins, Oxygen, Near infrared, Cell death, Visible radiation

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Proceedings Article | 2 June 2011 Paper

Fat tissue histological study at NIR laser treatment of the skin in vivo

Irina Yanina, Valery Tuchin, Nikita Navolokin, Olga Matveeva, Alla Bucharskaya, Galina Maslyakova

Proceedings Volume 8092, 809215 (2011) https://doi.org/10.1117/12.889178

KEYWORDS: Laser tissue interaction, Tissues, Skin, Laser irradiation, Absorption, Tissue optics, Near infrared, Statistical analysis, Laser applications, Indocyanine green

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