This paper performs detailed study of Raman scattering for platelets mixed with gold nanoparticles in presence with R6G molecules on quartz surface. Spectral properties of main spectral bands corresponding to proteins and dye in the complexes with gold nanoparticles have been performed. The perspectives SERS for applications in modern physics and biophotonics have been shown. Results of the study can be applied for SERS detection and investigation of blood components such as cells and platelets. Paper describes characteristic maxima of different cell components and its identification in platelets.
This paper describes detailed study of single human platelet and can be used for rapid and early structure changes and biomarkers identification in individuals with cardiovascular decease (CCD) pathology in vitro. The obtained data include analyzed Surface-enhanced Raman spectra (SERS) of human platelets taken from healthy individuals and individuals with cardiovascular pathology. Paper describes characteristic maxima of different cell components and its changes in platelets.
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