CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12836 > Article
Presentation
13 March 2024 Bioimaging enhanced by 2D materials and interpretable machine learning
Shengxi Huang
Author Affiliations +
Proceedings Volume PC12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis; PC128360G (2024) https://doi.org/10.1117/12.3007613
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Bioimaging techniques with molecular specific information will provide important insights into diagnosis, treatment, and understanding of disease pathology. To obtain molecular information, it is important to have high multiplexity and high specificity hyperspectral imaging, together with analysis techniques to interpret spectral signatures. This talk introduces pioneering discoveries and novel approaches to achieve these goals. I will introduce a new bioimaging mechanism, Raman imaging enhanced through 2D materials, an enhancement effect of molecular Raman fingerprints on the atomically-flat 2D material surfaces. It offers a new paradigm of biochemical sensing with high specificity, high multiplexity, and low noise. The selection rule for the 2D material substrates has been revealed, which is critical for device design. Hyperspectral imaging examples for brain tissues with Alzheimer’s disease will be discussed, where interpretable machine learning was further applied for new knowledge discovery. The works presented offer important guidelines to design high-performance biosensing and imaging devices, and are significant in fundamental material science and quantum science.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Shengxi Huang "Bioimaging enhanced by 2D materials and interpretable machine learning", Proc. SPIE PC12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis, PC128360G (13 March 2024); https://doi.org/10.1117/12.3007613
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
2D materials
Quantum machine learning
Biosensing
Design and modelling
Hyperspectral imaging
Raman spectroscopy
Pathology
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top