Cancer diagnosis using a conventional x-ray fluorescence camera with a cadmium-telluride detector

Eiichi Sato; Toshiyuki Enomoto; Osahiko Hagiwara; Abulajiang Abudurexiti; Koetsu Sato; Shigehiro Sato; Akira Ogawa; Jun Onagawa

doi:10.1117/12.893328

15 September 2011 Cancer diagnosis using a conventional x-ray fluorescence camera with a cadmium-telluride detector

Eiichi Sato, Toshiyuki Enomoto, Osahiko Hagiwara, Abulajiang Abudurexiti, Koetsu Sato, Shigehiro Sato, Akira Ogawa, Jun Onagawa

Author Affiliations +

Proceedings Volume 8143, Medical Applications of Radiation Detectors; 81430L (2011) https://doi.org/10.1117/12.893328
Event: SPIE Optical Engineering + Applications, 2011, San Diego, California, United States

Abstract

X-ray fluorescence (XRF) analysis is useful for mapping various atoms in objects. Bremsstrahlung X-rays are selected using a 3.0 mm-thick aluminum filter, and these rays are absorbed by indium, cerium and gadolinium atoms in objects. Then XRF is produced from the objects, and photons are detected by a cadmium-telluride detector. The Kα photons are discriminated using a multichannel analyzer, and the number of photons is counted by a counter card. The objects are moved and scanned by an x-y stage in conjunction with a two-stage controller, and X-ray images obtained by atomic mapping are shown on a personal computer monitor. The scan steps of the x and y axes were both 2.5 mm, and the photon-counting time per mapping point was 0.5 s. We carried out atomic mapping using the X-ray camera, and Kα photons from cerium and gadolinium atoms were produced from cancerous regions in nude mice.

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Eiichi Sato, Toshiyuki Enomoto, Osahiko Hagiwara, Abulajiang Abudurexiti, Koetsu Sato, Shigehiro Sato, Akira Ogawa, and Jun Onagawa "Cancer diagnosis using a conventional x-ray fluorescence camera with a cadmium-telluride detector", Proc. SPIE 8143, Medical Applications of Radiation Detectors, 81430L (15 September 2011); https://doi.org/10.1117/12.893328

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KEYWORDS

X-rays

Cerium

Photons

Gadolinium

Indium

Chemical species

Cameras

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