In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer

Peter J. Milne; Fabrice Manns; David B. Denham; Jean-Marie A. Parel; David S. Robinson M.D.

doi:10.1117/12.351001

22 June 1999 In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer

Peter J. Milne, Fabrice Manns, David B. Denham, Jean-Marie A. Parel, David S. Robinson M.D.

Author Affiliations +

Proceedings Volume 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX; (1999) https://doi.org/10.1117/12.351001
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Temperature increases and the resultant thermal field produced by the irradiation of ex vivo (porcine and human) and in vivo (porcine) tissue models appropriate to the treatment of human breast tissue using Nd:YAG (cw:60W) radiation delivered with an interstitial fiber optic probe were recorded with an array of fifteen 23 gauge needle thermocouple probes connected to a laboratory computer based data acquisition system. Using a stepwise decreasing power cycle to avoid tissue charring, acceptably symmetric thermal fields of repeatable volumetric dimensions were obtained. Reproducible thermal gradients and predictable tissue necrosis without carbonization could be induce din a three centimeter diameter region around the fiber probe during a single treatment lasting only 3 minutes. The time-dependence of the temperature rise of the thermocouples surrounding the LITT probe were quantitatively modeled with simple linear functions during the applied laser heating cycles.

Citation Download Citation

Peter J. Milne, Fabrice Manns, David B. Denham, Jean-Marie A. Parel, and David S. Robinson M.D. "In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer", Proc. SPIE 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, (22 June 1999); https://doi.org/10.1117/12.351001

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available