RA diagnostics applying optical tomography in frequency-domain

Alexander D. Klose; Viravuth Prapavat; Olaf Minet; Juergen Beuthan; Gerhard J. Mueller

doi:10.1117/12.297920

13 January 1998 RA diagnostics applying optical tomography in frequency domain

Alexander D. Klose, Viravuth Prapavat, Olaf Minet, Juergen Beuthan, Gerhard J. Mueller

Proceedings Volume 3196, Optical and Imaging Techniques for Biomonitoring III; (1998) https://doi.org/10.1117/12.297920
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

Our aim is to reconstruct the optical parameters in a slice of a finger joint phantom for further investigations about rheumatoid arthritis (RA). Therefore, we have developed a flexible NIR scanning system in order to collect amplitude and phase delay of photon density waves in frequency-domain. A cylindrical finger joint phantom was embedded in a container of Intralipid solution due to the application of an inverse method for infinite geometry. The joint phantom was investigated by a laser beam obtaining several projections. The average optical parameters of each projection was calculated. Using different reconstruction techniques, e.g. ART and SIRT with a special projection operator, we reconstructed the optical parameters in a slice. The projection operator can be heuristically described by a photon path density function of a homogeneous media with infinite geometry. Applied to an object with an unknown distribution of optical parameters it calculates the expectation value of the investigated object. The potentials and limits of these fast reconstruction methods will be presented.

Citation Download Citation

Alexander D. Klose, Viravuth Prapavat, Olaf Minet, Juergen Beuthan, and Gerhard J. Mueller "RA diagnostics applying optical tomography in frequency domain", Proc. SPIE 3196, Optical and Imaging Techniques for Biomonitoring III, (13 January 1998); https://doi.org/10.1117/12.297920

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
11 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

CITATIONS

Cited by 14 scholarly publications.

Explore citations on Lens.org

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Diagnostics

Optical tomography

Near infrared

RELATED CONTENT

Near-infrared Raman spectroscopy detects lung cancer
Proceedings of SPIE (January 18 2005)

In vivo multiphoton tomography of skin as a tool to...
Proceedings of SPIE (April 25 2005)

NIR confocal microscopy for painting diagnostics
Proceedings of SPIE (July 01 2009)

Spectral diagnosis of human coronary artery a clinical system...
Proceedings of SPIE (May 12 1995)

In vivo multiphoton tomography of inflammatory tissue and melanoma
Proceedings of SPIE (April 25 2005)

Measurement optimization for near-infrared optical tomography
Proceedings of SPIE (April 28 2005)

Numerical comparison of different penalty modified barrier functions for optical...
Proceedings of SPIE (February 23 2009)

Subscribe to Digital Library

Receive Erratum Email Alert

Keywords/Phrases

Search In:

Publication Years