Exocrine and endocrine testicular function during the treatment of experimental orchitis and nonspecific orchoepididymitis by low-energy laser radiation

Leonid L. Reznikov M.D.; Ludmila S. Pupkova; H. Bell; Alexander G. Murzin

doi:10.1117/12.209934

22 May 1995 Exocrine and endocrine testicular function during the treatment of experimental orchitis and nonspecific orchoepididymitis by low-energy laser radiation

Leonid L. Reznikov M.D., Ludmila S. Pupkova, H. Bell, Alexander G. Murzin

Author Affiliations +

Proceedings Volume 2391, Laser-Tissue Interaction VI; (1995) https://doi.org/10.1117/12.209934
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

Investigations into the biological effects of low-energy laser radiation (LLR) are characterized by a score of challenges, which are due primarily to a cascade of laser-induced and sometimes antagonistic processes. To investigate these processes on various biologic levels, we analyzed local and general effects of LLR on the exocrine and endocrine functions of the accessory sex glands in experimentally induced orchitis and orchoepididymitis in rabbits, and in clinical studies on male patients. The results indicate that LLR may alter the inflammatory response, including the exudative reaction, macrophage migration, and fibroblast activity. Furthermore, LLR may result in changes in serum concentrations of LH, FSH, and ACTH, prolactin, testosterone, cortisol and aldosterone. Some of these changes may be at least partially responsible for the well-known anti-inflammatory effects of LLR.

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Leonid L. Reznikov M.D., Ludmila S. Pupkova, H. Bell, and Alexander G. Murzin "Exocrine and endocrine testicular function during the treatment of experimental orchitis and nonspecific orchoepididymitis by low-energy laser radiation", Proc. SPIE 2391, Laser-Tissue Interaction VI, (22 May 1995); https://doi.org/10.1117/12.209934

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KEYWORDS

Laser therapeutics

Testis

Quantum cascade lasers

Inflammation

Biological research

Carbon monoxide

Connective tissue

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