In recent years, there has been a growing emphasis on the real-time detection and collection of airborne biothreats due to the challenges highlighted by events like the COVID-19 pandemic and the persistent concerns surrounding bioterrorism, bioweapons, and biowarfare in the realms of defense and national security. The study presents a solution to the limitations of inertia-based devices in capturing nanoscale biothreats, such as viral particles. It introduces a device that increases particle size by inducing water vapor condensation and heterogeneous nucleation on nanoparticles. Experimental results demonstrate its effectiveness in enlarging 0.4 µm polystyrene particles to approximately 2 µm. The device, featuring three segments, employs a stratified air and water flow and utilizes the principle that the mass diffusivity of water vapor in air surpasses the thermal diffusivity of air to create supersaturated conditions. Importantly, this device can seamlessly integrate with existing inertial-based systems, thereby enhancing their capability to capture nanoscale bioaerosols and improving collection and enrichment efficiency.
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