We present a new dynamic full-field optical coherence tomography (D-FF-OCT) imaging technique, which is self-referenced, vibration-insensitive and overcomes D-FF-OCT limitations near specular surfaces, named interface self-referencing D-FF-OCT (iSR-D-FF-OCT). In fibroblasts, retinal organoids, and corneal explants, we demonstrate imaging in the vicinity of reflective interfaces without fringe artefacts, in a live, label-free, non-invasive manner with sub-diffraction limited sectioning capacity within 3D samples. iSR-(D)-FF-OCT has a homogeneous contrast across the imaging field enabling flawless mosaicking. iSR-(D)-FF-OCT complements and is easily implemented on existing D-FF-OCT set-ups to cover a zero to several hundred micrometer depth range.
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