Adaptive glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view

Pedro Mecê; Jules Scholler; Kassandra Groux; Kate Grieve; Claude Boccara

doi:10.1117/12.2576689

5 March 2021 Adaptive glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view

Pedro Mecê, Jules Scholler, Kassandra Groux, Kate Grieve, Claude Boccara

Author Affiliations +

Proceedings Volume 11623, Ophthalmic Technologies XXXI; 1162306 (2021) https://doi.org/10.1117/12.2576689
Event: SPIE BiOS, 2021, Online Only

Abstract

The highest three-dimensional (3D) resolution possible in in-vivo retinal imaging is achieved by combining optical coherence tomography (OCT) and adaptive optics. However, this combination brings important limitations, such as small field-of-view and complex, cumbersome systems, preventing so far the translation of this technology from the research lab to clinics. Here, we mitigate these limitations by combining our compact time-domain full-field OCT (FFOCT) with a multi-actuator adaptive lens positioned just in front of the eye, in a technique we call the adaptive-glasses wavefront sensorless approach. Through this approach, we demonstrate that ocular aberrations can be corrected, increasing the FFOCT signal-to-noise ratio and enabling imaging of different retinal layers with a 2μm x 2μm x 8μm resolution over a 5° x 5° field-of-view, without major anisoplanatism influence.

Conference Presentation

Citation Download Citation

Pedro Mecê, Jules Scholler, Kassandra Groux, Kate Grieve, and Claude Boccara "Adaptive glasses wavefront sensorless full-field OCT for high-resolution retinal imaging over a wide field-of-view", Proc. SPIE 11623, Ophthalmic Technologies XXXI, 1162306 (5 March 2021); https://doi.org/10.1117/12.2576689

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