Our work is a first step towards clinically validating 3D T1ρ MRI to be used for routine clinical diagnosis of Osteoarthritis (OA) and for measuring the progression of the disease and its response to therapy in OA clinical trials. Reproducibility of T1ρ values(ms) were first measured using a phantom and then on heathy participants using both Siemens 3T Prisma and GE 3T Architect clinical scanners. Intra- and inter-vendor variability was assessed on each patient and scanner with 3 test-retest scans.
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