Recently, backscattering polarization images have been used to explore the microstructures of biological tissues. A proposed study is presented for classifying different samples including a set of 7.4 pH Phosphate-buffered saline (PBS), plasma fibronectin (FN), fibronectin fibril assembly at 0.25 ml/h (FFN 25), and fibronectin fibril assembly at 0.48 ml/h (FFN 48) based on the Mueller matrix backscattering images. The research showed that the diagonal components values m22, m33, and m44 of PBS are considerably higher than those of the fibrillated fibronectin samples (i.e. FN, FFN 25 and FFN 48). In other words, PBS samples are more isotropic than the others whereas FFN 25 and FFN 48 are anisotropic. Furthermore, the frequency distribution histograms (FDHs) of all Mueller matrix elements are evaluated for yielding critical explicit structural information in the form of distinct values that may be used to distinguish four samples. The results also indicated that FFN 48 has the most noticeable depolarization properties. As a consequence, this approach has shown to be an effective method of assessing microstructural research.
Liver cancer is currently ranked to be the sixth most common cancer worldwide. Indeed,
hepatocellular carcinoma (HCC) is the most frequent type of liver cancer. In this study, we
applied an optical polarization system utilizing the Stokes-Mueller matrix to differentiate the
HCC tissues with normal ones based on optical characteristics decomposed from the interaction
of cancerous and normal tissues with polarized light. Nine optical parameters from tissues were
extracted, specifically LB orientation angle (α), the LB phase retardance (β), the CB optical
rotation angle (γ), the LD orientation angle (θd), the linear dichroism (D), the circular
dichroism (R), the degrees of linear depolarization (e1 and e2), the degree of circular
depolarization (e3), and the depolarization index (Δ). The experimental results showed that the
orientation angle of linear birefringence (α), linear dichroism (D), and orientation angle of
linear dichroism (θd) have the differences between cancerous and normal tissues. It promises a
practical penetration to the optical characteristic of liver cancer based on Stokes-Mueller matrix
polarimetry.
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