With the advent of optical methods for stimulation and functional recording of neuronal activity in the brain, there is a growing need for fully flexible, ultracompact photonic devices for light delivery and light collection in brain tissue. In this paper, we will discuss our recent advances in designing a flexible optoelectronic neural implant platform that integrates passive and active optical components with electrical recording functionality. We leverage the exquisite optical and electrical insulation properties Parylene C, a biocompatible and flexible polymer to realize a fully functional optoelectrical neural interface.
To use optical techniques deep in tissue, implantable microdevices which can collect and deliver light with high efficiency are needed. Flexible polymer devices can reduce tissue damage. Here, we demonstrate a fully-flexible, low-loss (3.2 dB/cm @ 680 nm), broadband (450-680 nm) integrated photonic platform composed entirely of Parylene C and PDMS. Using this platform, we demonstrate devices with an array of 6 waveguides and 1.3 cm total length. We integrate bare laser diode chips (220 x 220 μm, λ= 680 nm) to realize a light delivery system for optogenetics. Simulation, characterization, and biological demonstration will be discussed.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.