Dr. Matthew Brenner Profile

Dr. Matthew Brenner

Professor, Pulmonary and Critical Care Medicine UC at Beckman Laser Institute and Medical Clinic

SPIE Involvement:

Conference Program Committee | Author | Editor

Publications (36)

Proceedings Article | 17 March 2023 Presentation

Deep learning accelerated quantitative assessment for optical coherence tomography images of acute chlorine gas inhalation injury in a rabbit model

Zhikai Zhu, Hongqiu Lei, Raksha Sreeramachandra Murthy, Theodore Nguyen, Katelyn Dilley, Donggyoon Hong, Xiao Gao, Matthew Brenner, Zhongping Chen

Proceedings Volume 12354, 123540M (2023) https://doi.org/10.1117/12.2668720

KEYWORDS: Optical coherence tomography, Chlorine gas, Injuries, Deep learning, In vivo imaging, Chlorine, Nervous system, Ultrasonography, Tomography, Spatial resolution

Read Abstract +

Proceedings Article | 7 March 2022 Presentation

In-vivo airway compliance analysis of acute chlorine gas inhalation injury in rabbit model

Zhikai Zhu, George Philipopoulos, Melody Doosty, Jangwoen Lee, David Mukai, Xiao Gao, Sari Mahon, Matthew Brenner, Livia Veress, Carl White, Zhongping Chen

Proceedings Volume PC11937, PC119370E (2022) https://doi.org/10.1117/12.2610423

KEYWORDS: In vivo imaging, Injuries, Chlorine gas, Imaging systems, Vertical cavity surface emitting lasers, Optical coherence tomography, Tissues, Pathogens, Light sources, Image segmentation

Read Abstract +

Proceedings Article | 5 March 2021 Presentation

Wide-field mapping of upper airway cilia dynamics using spectrally encoded interferometric microscopy

Zhikai Zhu, Jason Chen, Yusi Miao, David Mukai, George Philipopoulos, Melina Doosty, Jangwoen Lee, Sari Mahon, Matthew Brenner, Brian J. Wong, Zhongping Chen

Proceedings Volume 11627, 1162708 (2021) https://doi.org/10.1117/12.2578007

KEYWORDS: Microscopy, Interferometry, Doppler effect, Visualization, Wave propagation, Viruses, Spatial resolution, Pathogens, Particles, Optical imaging

Read Abstract +

Proceedings Article | 5 March 2021 Presentation

In-vivo analysis of acute chlorine gas inhalation injury using optical coherence tomography (OCT) in rabbit model

Zhikai Zhu, Yusi Miao, George Philipopoulos, Melody Doosty, Wenqi He, Jianing Tang, Jangwoen Lee, David Mukai, Fengyi Zhang, Saijun Qiu, Jing Cao, Xiao Gao, Sari Mahon, Livia Veress, Matthew Brenner, Carl White, Zhongping Chen

Proceedings Volume 11620, 1162007 (2021) https://doi.org/10.1117/12.2577927

KEYWORDS: Optical coherence tomography, Injuries, Chlorine gas, In vivo imaging, Tissues, Imaging systems, Vertical cavity surface emitting lasers, Bronchoscopy, Visualization, Diagnostics

Read Abstract +

Proceedings Article | 6 March 2020 Presentation + Paper

Assessment of toxin-induced airway injury and therapeutic effects in a rat model by optical coherence tomography

Ryan Cheung, Yusi Miao, Andy Choi, Carl White, Matthew Brenner, Zhongping Chen

Proceedings Volume 11213, 112130G (2020) https://doi.org/10.1117/12.2546356

KEYWORDS: Image segmentation, Optical coherence tomography, 3D modeling, Neural networks, Data modeling, Biomedical optics, Convolutional neural networks, Injuries, Machine vision, Computer vision technology

Read Abstract +

SPIE Journal Paper | 24 March 2018 Open Access

Quantitative real-time optical imaging of the tissue metabolic rate of oxygen consumption

Michael Ghijsen, Griffin Lentsch, Sylvain Gioux, Matthew Brenner, Anthony Durkin, Bernard Choi, Bruce Tromberg

JBO, Vol. 23, Issue 03, 036013, (March 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.3.036013

KEYWORDS: Oxygen, Tissues, Mode conditioning cables, Tissue optics, Cyanide, Chromophores, Optical imaging, Blood circulation, Blood, Speckle

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 14 March 2018 Presentation

Automated 3D reconstruction and evaluation of methyl isocyanate-induced airway injury in a rat model using a miniature optical coherence endoscopy probe (Conference Presentation)

Yusi Miao, Joseph Jing, Vineet Desai, Yueqiao Qu, Jacqueline Rioux, Rhonda Garlick, Livia Veress, Sari Mahon, Matthew Brenner, Carl White, Zhongping Chen

Proceedings Volume 10470, 104700E (2018) https://doi.org/10.1117/12.2287289

KEYWORDS: Endoscopy, Optical coherence tomography, 3D modeling, Industrial chemicals, Animal model studies, Injuries, Coherence (optics), Image segmentation, 3D image processing, Stereoscopy

Read Abstract +

Proceedings Article | 8 March 2016 Presentation + Paper

Optical coherence tomography imaging to analyze biofilm thickness from distal to proximal regions of the endotracheal tubes

Robert Dunn, Andrew Heidari, Samer Moghaddam, Mengke Zhang, Changhoon Han, Kyung-Jin Oh, Steve Leven, Matthew Brenner, Carl Genberg, Zhongping Chen

Proceedings Volume 9691, 96911G (2016) https://doi.org/10.1117/12.2213247

KEYWORDS: Optical coherence tomography, Coherence imaging, Optical imaging, Analytical research, Biological research, Translational research, Lung, In vivo imaging, Tomography, Image segmentation, Bacteria, Visualization, Image processing, Image analysis, Image compression, Biomedical engineering

Read Abstract +

SPIE Journal Paper | 19 February 2016 Open Access

Errata: Visualizing biofilm formation in endotracheal tubes using endoscopic three-dimensional optical coherence tomography

Andrew Heidari, Samer Moghaddam, Kimberly Truong, Lidek Chou, Carl Genberg, Matthew Brenner, Zhongping Chen

JBO, Vol. 21, Issue 02, 029802, (February 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.2.029802

KEYWORDS: Visualization, Endoscopy, Optical coherence tomography, Biomedical engineering, Biomedical optics, Health sciences, Roads, Pulmonology, Lanthanum

DOWNLOAD PAPER

SPIE Journal Paper | 22 December 2015 Open Access

Visualizing biofilm formation in endotracheal tubes using endoscopic three-dimensional optical coherence tomography

Andrew E. Heidari, Samer Moghaddam, Kimberly Truong, Li-Dek Chou, Carl Genberg, Matthew Brenner, Zhongping Chen

JBO, Vol. 20, Issue 12, 126010, (December 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.126010

KEYWORDS: Optical coherence tomography, Scanning electron microscopy, Visualization, Bacteria, Endoscopy, Biological research, Image segmentation, Polymers, Diagnostics, Head-mounted displays

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 May 2014 Open Access

Noninvasive optical cytochrome c oxidase redox state measurements using diffuse optical spectroscopy

Jangwoen Lee, Jae Gwan Kim, Sari Mahon, David Mukai, David Yoon, Gerry Boss, Steven Patterson, Gary Rockwood, Gary Isom, Matthew Brenner

JBO, Vol. 19, Issue 05, 055001, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.5.055001

KEYWORDS: Oxygen, Tissues, Absorption, Blood, Tissue optics, Scattering, Near infrared, Magnesium, Scanning electron microscopy, In vivo imaging

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 24 March 2014 Open Access

In vivo detection of inhalation injury in large airway using three-dimensional long-range swept-source optical coherence tomography

Lidek Chou, Andriy Batchinsky, Slava Belenkiy, Joseph Jing, Tirunelvil Ramalingam, Matthew Brenner, Zhongping Chen

JBO, Vol. 19, Issue 03, 036018, (March 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.3.036018

KEYWORDS: Optical coherence tomography, Imaging systems, Injuries, Range imaging, 3D image processing, In vivo imaging, 3D image reconstruction, Tissues, Bragg cells, Cartilage

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 October 2012 Open Access

Noninvasive monitoring of treatment response in a rabbit cyanide toxicity model reveals differences in brain and muscle metabolism

Jae Gwan Kim, Jangwoen Lee, Sari Mahon, David Mukai, Steven Patterson, Gerry Ross, Bruce Tromberg, Matthew Brenner

JBO, Vol. 17, Issue 10, 105005, (October 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.10.105005

KEYWORDS: Brain, Rhodamine B, Sodium, Toxicity, Tissues, Cyanide, Mode conditioning cables, Blood, In vivo imaging, Tissue optics

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 9 February 2012 Paper

Miniature integrated optical coherence tomography (OCT) - ultrasound (US) probe for intravascular imaging

Jiawen Li, Jiechen Yin, Xiang Li, Joe Jing, David Mukai, Sari Mahon, Ahmad Edris, Khiet Hoang, K. Kirk Shung, Matthew Brenner, Jagat Narula, Qifa Zhou, Pranav Patel, Zhongping Chen

Proceedings Volume 8207, 82073X (2012) https://doi.org/10.1117/12.905707

KEYWORDS: Optical coherence tomography, Arteries, Transducers, Ultrasonography, In vivo imaging, Intravascular ultrasound, Tomography, Imaging systems, Integrated optics, Coherence (optics)

Read Abstract +

SPIE Journal Paper | 1 October 2011 Open Access

Investigating in vivo airway wall mechanics during tidal breathing with optical coherence tomography

Claire Robertson, Zhongping Chen, Steven George, Sang-Won Lee, Yeh-Chan Ahn, Sari Mahon, Matthew Brenner

JBO, Vol. 16, Issue 10, 106011, (October 2011) https://doi.org/10.1117/12.10.1117/1.3642006

KEYWORDS: Optical coherence tomography, Tissues, In vivo imaging, Mechanics, Natural surfaces, Motion analysis, Image processing, Protactinium, Spatial resolution, Endoscopy

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 June 2011 Open Access

Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging

Jiechen Yin, Jiawen Li, Zhongping Chen, Xiang Li, Kirk Shung, Qifa Zhou, Joseph Jing, David Mukai, Sari Mahon, Matthew Brenner, Ahmad Edris, Ahmad Khiet Hoang, Jagat Narula

JBO, Vol. 16, Issue 06, 060505, (June 2011) https://doi.org/10.1117/12.10.1117/1.3589097

KEYWORDS: Optical coherence tomography, Ultrasonography, In vivo imaging, Transducers, Imaging systems, Lithium, Data acquisition, In vitro testing, Arteries, Intravascular ultrasound

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 16 February 2011 Paper

Integrated optical coherence tomography - ultrasound system and miniaturized probes for intravascular imaging

Jiechen Yin, Xiang Li, Joe Jing, Changhong Hu, Qifa Zhou, Tanya Burney, David Mukai, Sari Mahon, Ahmad Edris, Khiet Hoang, K. Kirk Shung, Matthew Brenner, Jagat Narula, Zhongping Chen

Proceedings Volume 7889, 788918 (2011) https://doi.org/10.1117/12.875128

KEYWORDS: Optical coherence tomography, Imaging systems, Transducers, Ultrasonography, In vivo imaging, Data acquisition, Intravascular ultrasound, Integrated optics, Coherence (optics), Tomography

Read Abstract +

Proceedings Article | 20 February 2010 Paper

In vivo early detection of smoke-induced airway injury using 3-dimensional swept source optical coherence tomography

Jiechen Yin, Gangjun Liu, Jun Zhang, Lingfeng Yu, Sari Mahon, David Mukai, Matthew Brenner, Zhongping Chen

Proceedings Volume 7554, 755408 (2010) https://doi.org/10.1117/12.841346

KEYWORDS: Optical coherence tomography, Injuries, Image processing, 3D image processing, Microelectromechanical systems, Reconstruction algorithms, In vivo imaging, 3D modeling, 3D image reconstruction, Endoscopes

Read Abstract +

SPIE Journal Paper | 1 January 2010 Open Access

Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring

Matthew Brenner, Sari Mahon, Jangwoen Lee, Jae Gwan Kim, David Mukai, Seth Goodman, Kelly Kreuter, Rebecca Ahdout, Othman Mohammad, Vijay Sharma, William Blackledge, Gerry Boss

JBO, Vol. 15, Issue 01, 017001, (January 2010) https://doi.org/10.1117/12.10.1117/1.3290816

KEYWORDS: Cyanide, Blood, Tissues, Control systems, Toxicity, Molecules, Animal model studies, Diffuse optical spectroscopy, Absorption, Scattering

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 January 2010 Open Access

Linking optics and mechanics in an in vivo model of airway fibrosis and epithelial injury

Christopher Raub, Sari Mahon, Navneet Narula, Bruce Tromberg, Matthew Brenner, Steven George

JBO, Vol. 15, Issue 01, 015004, (January 2010) https://doi.org/10.1117/12.10.1117/1.3322296

KEYWORDS: Second-harmonic generation, Collagen, Tissues, Injuries, Mechanics, In vivo imaging, Image segmentation, Tissue optics, Blood vessels, Biomedical optics

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 November 2009 Open Access

In vivo early detection of smoke-induced airway injury using three-dimensional swept-source optical coherence tomography

Jiechen Yin, Gangjun Liu, Jun Zhang, Lingfeng Yu, Sari Mahon, David Mukai, Matthew Brenner, Zhongping Chen

JBO, Vol. 14, Issue 06, 060503, (November 2009) https://doi.org/10.1117/12.10.1117/1.3268775

KEYWORDS: Optical coherence tomography, 3D image processing, Injuries, Microelectromechanical systems, Cartilage, Reconstruction algorithms, 3D image reconstruction, In vivo imaging, Image processing, Image quality

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 November 2009 Open Access

In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance

Tuqiang Xie, Gangjun Liu, Kelly Kreuter, Sari Mahon, Henri Colt, David Mukai, George Peavy, Zhongping Chen, Matthew Brenner

JBO, Vol. 14, Issue 06, 064045, (November 2009) https://doi.org/10.1117/12.10.1117/1.3275478

KEYWORDS: Optical coherence tomography, Tumors, In vivo imaging, Imaging systems, 3D image processing, Endoscopy, Chest, Tissues, GRIN lenses, Lung

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 July 2009 Open Access

Detection and monitoring of early airway injury effects of half-mustard (2-chloroethylethylsulfide) exposure using high-resolution optical coherence tomography

Kelly Kreuter, Sari Mahon, David Mukai, Jianping Su, Woonggyu Jung, Navneet Narula, S. Guo, Nicole Wakida, Christopher Raub, Michael Berns, Steven George, Zhongping Chen, Matthew Brenner

JBO, Vol. 14, Issue 04, 044037, (July 2009) https://doi.org/10.1117/12.10.1117/1.3210775

KEYWORDS: Injuries, Optical coherence tomography, Imaging systems, Blistering agents, Tissues, Lung, Animal model studies, Fiber optics, Image resolution, Luminescence

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 July 2009 Open Access

Broadband diffuse optical spectroscopy assessment of hemorrhage- and hemoglobin-based blood substitute resuscitation

Jangwoen Lee, Jae Gwan Kim, Sari Mahon, Bruce Tromberg, David Mukai, Kelly Kreuter, Darin Saltzman, Renee Patino, Robert Goldberg, Matthew Brenner

JBO, Vol. 14, Issue 04, 044027, (July 2009) https://doi.org/10.1117/12.10.1117/1.3200932

KEYWORDS: Blood, Tissues, Rhodamine B, Tissue optics, Scattering, Oxygen, Diffuse optical spectroscopy, In vivo imaging, Near infrared, Surface plasmons

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 July 2009 Open Access

Errata: Multimodality bronchoscopic imaging of tracheopathica osteochondroplastica

Henri Colt, Septimiu Murgu, Yeh-Chan Ahn, Matthew Brenner

JBO, Vol. 14, Issue 04, 049801, (July 2009) https://doi.org/10.1117/12.10.1117/1.3223334

KEYWORDS: Medicine, Health sciences, Roads, Head

DOWNLOAD PAPER

SPIE Journal Paper | 1 May 2009 Open Access

Use of an oxygen-carrying blood substitute to improve intravascular optical coherence tomography imaging

Khiet Hoang, Ahamd Edris, Jianping Su, David Mukai, Sari Mahon, Artiom Petrov, Morton Kern, Chowdhury Ahsan, Zhongping Chen, Bruce Tromberg, Jagat Narula, Matthew Brenner

JBO, Vol. 14, Issue 03, 034028, (May 2009) https://doi.org/10.1117/12.10.1117/1.3153895

KEYWORDS: Optical coherence tomography, Blood, Coherence imaging, Image quality, Light scattering, Optical imaging, Signal attenuation, Scattering, Image resolution, Oxygen

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 May 2009 Open Access

Multimodality bonchoscopic imaging of tracheopathica osteochondroplastica

Henri Colt, Septimiu Murgu, Yeh-Chan Ahn, Matthew Brenner

JBO, Vol. 14, Issue 03, 034035, (May 2009) https://doi.org/10.1117/12.10.1117/1.3155524

KEYWORDS: Imaging systems, Optical coherence tomography, Bronchoscopy, Ultrasonography, Image resolution, Tissues, Biopsy, Diagnostics, Bone, Cartilage

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 20 February 2009 Paper

3D in vivo swept source endoscopic OCT based on rigid GRIN lens rod probe

Gangjun Liu, Tuqiang Xie, Jun Zhang, George Peavy, Matthew Brenner, Zhongping Chen

Proceedings Volume 7168, 716812 (2009) https://doi.org/10.1117/12.809624

KEYWORDS: Optical coherence tomography, GRIN lenses, In vivo imaging, Endoscopy, 3D image processing, Signal to noise ratio, Mirrors, Tissues, Lung, 3D image reconstruction

Read Abstract +

SPIE Journal Paper | 1 November 2008 Open Access

Tissue hemoglobin monitoring of progressive central hypovolemia in humans using broadband diffuse optical spectroscopy

Jangwoen Lee, Jae Gwan Kim, Sari Mahon, Bruce Tromberg, Kathy Ryan, Victor Convertino, Caroline Rickards, Kathryn Osann, Matthew Brenner

JBO, Vol. 13, Issue 06, 064027, (November 2008) https://doi.org/10.1117/12.10.1117/1.3041712

KEYWORDS: Tissues, Blood, Tissue optics, Rhodamine B, Heart, Oxygen, Tolerancing, Diffuse optical spectroscopy, Hemodynamics, Injuries

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 May 2008 Open Access

Real-time swept source optical coherence tomography imaging of the human airway using a microelectromechanical system endoscope and digital signal processor

Jianping Su, Jun Zhang, Lingfeng Yu, Henri Colt, Matthew Brenner, Zhongping Chen

JBO, Vol. 13, Issue 03, 030506, (May 2008) https://doi.org/10.1117/12.10.1117/1.2938700

KEYWORDS: Digital signal processing, Optical coherence tomography, Endoscopes, Signal processing, Microelectromechanical systems, 3D image processing, Image processing, Coherence imaging, 3D acquisition, Signal detection

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 May 2008 Open Access

In vivo optical coherence tomography detection of differences in regional large airway smoke inhalation induced injury in a rabbit model

Matthew Brenner, Kelly Kreuter, Johnny Ju, Sari Mahon, Lillian Tseng, David Mukai, Tanya Burney, Shuguang Guo, Jiangping Su, Andrew Tran, Andriy Batchinsky, Leopoldo Cancio, Navneet Narula, Zhongping Chen

JBO, Vol. 13, Issue 03, 034001, (May 2008) https://doi.org/10.1117/12.10.1117/1.2939400

KEYWORDS: Optical coherence tomography, Injuries, In vivo imaging, Fiber optics, Blood, Statistical analysis, GRIN lenses, Image resolution, Veins, Instrument modeling

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 September 2007 Open Access

Detection of acute smoke-induced airway injury in a New Zealand white rabbit model using optical coherence tomography

Matthew Brenner, Kelly Kreuter, David Mukai, Tanya Burney, Shuguang Guo, Jianping Su, Sari Mahon, Andrew Tran, Lillian Tseng, Johnny Ju, Zhongping Chen

JBO, Vol. 12, Issue 05, 051701, (September 2007) https://doi.org/10.1117/12.10.1117/1.2798637

KEYWORDS: Optical coherence tomography, Injuries, Control systems, Fiber optics, Blood, In vivo imaging, Animal model studies, Cartilage, Scanning electron microscopy, GRIN lenses

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 March 2007 Open Access

Hemoglobin measurement patterns during noninvasive diffuse optical spectroscopy monitoring of hypovolemic shock and fluid replacement

Jangwoen Lee, Albert Cerussi, Darin Saltzman, Tom Waddington, Bruce Tromberg, Matthew Brenner

JBO, Vol. 12, Issue 02, 024001, (March 2007) https://doi.org/10.1117/12.10.1117/1.2715189

KEYWORDS: Tissues, Blood, Tissue optics, Oxygen, Animal model studies, Hemodynamics, Near infrared spectroscopy, Diffuse optical spectroscopy, Resistance, Absorption

Read Abstract +

DOWNLOAD PAPER

SPIE Journal Paper | 1 September 2004 Open Access

Optical coherence tomography of malignancy in hamster cheek pouches

Erin Matheny, Nevine Hanna, Reza Mina-Araghi, Woong Jung, Zhongping Chen, Petra Wilder-Smith, Matthew Brenner

JBO, Vol. 9, Issue 05, (September 2004) https://doi.org/10.1117/12.10.1117/1.1783897

KEYWORDS: Optical coherence tomography, Tissues, In vivo imaging, Tumors, Control systems, Blood circulation, Image resolution, Tumor growth modeling, Diagnostics, Blood vessels

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 1 July 2004 Paper

Optical coherence tomography in pulmonary imaging: feasibility study

Woonggyu Jung, Jun Zhang, Petra Wilder-Smith, Minaaraghi Reza, Matthew Brenner, YongJin Shin, J. Stuart Nelson, Zhongping Chen

Proceedings Volume 5316, (2004) https://doi.org/10.1117/12.529824

KEYWORDS: Optical coherence tomography, Lung, Cancer, Endoscopy, Lung cancer, Animal model studies, Tumor growth modeling, Tissues, Fiber optics, Image resolution

Read Abstract +