Dr. Leonard Y. Nelson Profile

Dr. Leonard Y. Nelson

Director at Univ of Washington

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Author

Publications (22)

SPIE Journal Paper | 13 January 2021 Open Access

Optical pH measurement system using a single fluorescent dye for assessing susceptibility to dental caries (Erratum)

Manuja Sharma, Jasmine Graham, Philip Walczak, Ryan Nguyen, Lauren Lee, Matthew Carson, Leonard Nelson, Shwetak Patel, Zheng Xu, Eric Seibel

JBO, Vol. 26, Issue 01, 019801, (January 2021) https://doi.org/10.1117/12.10.1117/1.JBO.26.1.019801

KEYWORDS: Optical testing, Dental caries, Photonics, Microbiology, Mechanical engineering, Dentistry, Computing systems, Computer engineering, Biochemistry

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Proceedings Article | 20 February 2020 Paper

Rapid detection of Escherichia coli in aqueous samples by metabolic induced change in pH

Noah Baker, Leonard Nelson, Eric Seibel

Proceedings Volume 11233, 112331E (2020) https://doi.org/10.1117/12.2545283

KEYWORDS: Bacteria, Luminescence, Contamination, Pathogens, Calibration, Glucose, Water contamination, Fluorescence spectroscopy, Biological detection systems, Chemical detection

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Proceedings Article | 7 March 2019 Presentation

Fluorescein based optical detection of oral pH (Conference Presentation)

Manuja Sharma, Jasmine Graham, Philip Walczak, Ryan Nguyen, Lauren Lee, Matthew Carson, Alireza Sadr, Zheng Xu, Len Nelson, Shwetak Patel, Eric Seibel

Proceedings Volume 10857, 108570B (2019) https://doi.org/10.1117/12.2511219

KEYWORDS: Bacteria, Optical testing, Luminescence, Mouth, Teeth, Dental caries, Fiber optics tests, Fiber optics, Fiber couplers, Light emitting diodes

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SPIE Journal Paper | 8 January 2019 Open Access

Optical pH measurement system using a single fluorescent dye for assessing susceptibility to dental caries

Manuja Sharma, Jasmine Graham, Philip Walczak, Ryan Nguyen, Lauren Lee, Matthew Carson, Leonard Nelson, Shwetak Patel, Zheng Xu, Eric Seibel

JBO, Vol. 24, Issue 01, 017001, (January 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.1.017001

KEYWORDS: Teeth, Calibration, Dental caries, Optical testing, Light emitting diodes, Luminescence, In vivo imaging, Fiber optics, Spectroscopy, In vitro testing

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Proceedings Article | 9 February 2018 Presentation + Paper

Optical measurement of acidification of human dental plaque in vitro

Jasmine Graham, Leonard Nelson, Eric Seibel

Proceedings Volume 10473, 104730A (2018) https://doi.org/10.1117/12.2286654

KEYWORDS: Dental caries, Rhodamine B, In vitro testing, Optical testing, Bacteria, Teeth, Spectroscopy, Molecules

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Proceedings Article | 24 February 2015 Paper

Real-time porphyrin detection in plaque and caries: a case study

Mari-Alina Timoshchuk, Jeremy Ridge, Amanda Rugg, Leonard Nelson, Amy Kim, Eric Seibel

Proceedings Volume 9306, 93060C (2015) https://doi.org/10.1117/12.2081016

KEYWORDS: Luminescence, Dental caries, Teeth, Atrial fibrillation, Tissues, Natural surfaces, Optical filters, Reflectivity, Visualization, X-rays

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SPIE Journal Paper | 15 July 2014 Open Access

Target-to-background enhancement in multispectral endoscopy with background autofluorescence mitigation for quantitative molecular imaging

Chenying Yang, Vivian Hou, Emily Girard, Leonard Nelson, Eric Seibel

JBO, Vol. 19, Issue 07, 076014, (July 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.7.076014

KEYWORDS: Atrial fibrillation, Tissues, Luminescence, Brain, Endoscopy, Esophagus, Tumors, Molecular imaging, Signal detection, Imaging systems

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Proceedings Article | 4 March 2014 Paper

Scanning Fiber Endoscope with multiple fluorescence-reflectance imaging channels for guiding biopsy

Chenying Yang, Vivian Hou, Leonard Nelson, Richard Johnston, C. David Melville, Eric Seibel

Proceedings Volume 8936, 89360R (2014) https://doi.org/10.1117/12.2038544

KEYWORDS: Luminescence, Endoscopes, Endoscopy, Biopsy, Cancer, Fiber lasers, Reflectivity, Image resolution, Neodymium, Imaging systems

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Proceedings Article | 4 March 2014 Paper

Multi-spectral scanning fiber endoscope with concurrent autofluorescence mitigation for enhanced target-to-background ratio imaging

Chenying Yang, Vivian Hou, Leonard Nelson, Richard Johnston, C. David Melville, Eric Seibel

Proceedings Volume 8927, 89270I (2014) https://doi.org/10.1117/12.2038553

KEYWORDS: Atrial fibrillation, Luminescence, Tissues, Endoscopes, Detection and tracking algorithms, Signal detection, Multispectral imaging, Endoscopy, Target detection, Molecular imaging

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Proceedings Article | 3 March 2014 Paper

The development of a simplified epithelial tissue phantom for the evaluation of an autofluorescence mitigation algorithm

Vivian Hou, Chenying Yang, Leonard Nelson, Eric Seibel

Proceedings Volume 8945, 894506 (2014) https://doi.org/10.1117/12.2040167

KEYWORDS: Atrial fibrillation, Collagen, Algorithm development, Tissues, Esophagus, Luminescence, Endoscopes, Detection and tracking algorithms, In vivo imaging, Biopsy

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Proceedings Article | 18 February 2014 Paper

Guided fluorescence diagnosis of childhood caries: preliminary measures correlate with depth of carious decay

Mari-Alina Timoshchuk, Liang Zhang, Brian Dickinson, Jeremy Ridge, Amy Kim, Camille Baltuck, Leonard Nelson, Joel Berg, Eric Seibel

Proceedings Volume 8929, 892904 (2014) https://doi.org/10.1117/12.2041648

KEYWORDS: Teeth, Dental caries, Atrial fibrillation, Visualization, Luminescence, Laser dentistry, Imaging spectroscopy, Prototyping, In vivo imaging, Spectroscopy

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SPIE Journal Paper | 28 August 2013 Open Access

Trimodal detection of early childhood caries using laser light scanning and fluorescence spectroscopy: clinical prototype

Liang Zhang, Amy Kim, Jeremy Ridge, Leonard Nelson, Joel Berg, Eric Seibel

JBO, Vol. 18, Issue 11, 111412, (August 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.11.111412

KEYWORDS: Atrial fibrillation, Luminescence, Teeth, Dental caries, Prototyping, Reflectivity, Fluorescence spectroscopy, In vivo imaging, Spectroscopes, Spectroscopy

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SPIE Journal Paper | 21 August 2013 Open Access

Mitigating fluorescence spectral overlap in wide-field endoscopic imaging

Chenying Yang, Vivian Hou, Leonard Nelson, Eric Seibel

JBO, Vol. 18, Issue 08, 086012, (August 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.8.086012

KEYWORDS: Luminescence, Phase modulation, Chromium, Signal detection, Multispectral imaging, Endoscopy, Reflectivity, In vivo imaging, Detection and tracking algorithms, Esophagus

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Proceedings Article | 25 March 2013 Paper

Multimodal optical device for early childhood caries: a clinical prototype

Liang Zhang, Jeremy Ridge, Leonard Nelson, Joel Berg, Eric Seibel

Proceedings Volume 8566, 856603 (2013) https://doi.org/10.1117/12.2006240

KEYWORDS: Atrial fibrillation, Teeth, Dental caries, Luminescence, Prototyping, In vivo imaging, Imaging systems, Fluorescence spectroscopy, Spectroscopy, Imaging spectroscopy

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Proceedings Article | 25 March 2013 Paper

Laser investigation of the non-uniformity of fluorescent species in dental enamel

Stephanie Tran, Jeremy Ridge, Leonard Nelson, Eric Seibel

Proceedings Volume 8566, 85660L (2013) https://doi.org/10.1117/12.2002519

KEYWORDS: Etching, Luminescence, Atrial fibrillation, Laser dentistry, Scanning electron microscopy, Collagen, Semiconductor lasers, Teeth, Dental caries, Tissues

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Proceedings Article | 28 February 2013 Paper

Color-matched esophagus phantom for fluorescent imaging

Chenying Yang, Vivian Hou, Leonard Nelson, Eric Seibel

Proceedings Volume 8583, 85830F (2013) https://doi.org/10.1117/12.2000834

KEYWORDS: Esophagus, Luminescence, Tissues, Tissue optics, Reflectivity, Latex, Endoscopes, Endoscopy, Molecular imaging, Natural surfaces

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SPIE Journal Paper | 12 February 2013 Open Access

Color-matched and fluorescence-labeled esophagus phantom and its applications

Chenying Yang, Vivian Hou, Leonard Nelson, Eric Seibel

JBO, Vol. 18, Issue 02, 026020, (February 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.2.026020

KEYWORDS: Esophagus, Luminescence, Reflectivity, Tissue optics, Tissues, Endoscopes, Latex, Endoscopy, Molecular imaging, Natural surfaces

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SPIE Journal Paper | 17 July 2012 Open Access

Spectrally enhanced imaging of occlusal surfaces and artificial shallow enamel erosions with a scanning fiber endoscope

Liang Zhang, Leonard Nelson, Eric Seibel

JBO, Vol. 17, Issue 7, 076019, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.076019

KEYWORDS: Scattering, Teeth, Light scattering, Adhesives, Scanning electron microscopy, Endoscopes, Image enhancement, Laser scattering, Natural surfaces, Monte Carlo methods

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Proceedings Article | 1 February 2012 Paper

Spectrally enhanced image resolution of tooth enamel surfaces

Liang Zhang, Leonard Nelson, Joel Berg, Eric Seibel

Proceedings Volume 8208, 82080F (2012) https://doi.org/10.1117/12.914273

KEYWORDS: Teeth, Scattering, Light scattering, Image resolution, Backscatter, Laser dentistry, Monte Carlo methods, Natural surfaces, Scanning electron microscopy, Atrial fibrillation

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SPIE Journal Paper | 1 July 2011 Open Access

Red-shifted fluorescence of sound dental hard tissue

Liang Zhang, Leonard Nelson, Eric Seibel

JBO, Vol. 16, Issue 07, 071411, (July 2011) https://doi.org/10.1117/12.10.1117/1.3606572

KEYWORDS: Luminescence, Teeth, Spectroscopy, Raman scattering, Absorption, Fiber lasers, Optical filters, Semiconductor lasers, Laser dentistry, Tissue optics

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Proceedings Article | 14 September 1998 Paper

Lamp-life predictive model for avionics backlights

Richard Webster, Leonard Nelson

Proceedings Volume 3363, (1998) https://doi.org/10.1117/12.321792

KEYWORDS: Lamps, Mathematical modeling, Data modeling, Coating, Mercury, LCDs, Feedback loops, Feedback control, Electronics, Cockpit displays

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Proceedings Article | 1 December 1993 Paper

Digital imaging technology applied to crewstation display measurements

Leonard Nelson, John Green

Proceedings Volume 1988, (1993) https://doi.org/10.1117/12.164707

KEYWORDS: CCD cameras, Optical filters, Digital imaging, Video, Charge-coupled devices, Infrared radiation, Calibration, Cameras, Infrared imaging, Displays

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