This paper report the development of non-invasive multi-functional imaging system for dental applications. This system is capable of detecting: 1) autofluorescence of the enamel, 2) red porphyrin of plaque, 3) the 3D-tomography of the hard/soft tissues and 4) functional angiography of said 3D-tomography data. The imaging technique incorporates molecular imaging (via light-induced autofluorescence, or LAF), 3D-high-resolution structure (via optical coherence tomography, or OCT) and angiography (via functional OCT, or OCTA) into one single imaging probe and platform. This development is crucial for our future research that would look into possible links between our OCTA findings and other clinical indicator such as red-porphyrin of plaque, autofluorescence of enamel.
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