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Kuan Lu

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Proceedings Article | 16 March 2011 Paper

The impact of filtering direct-feedthrough on the x-space theory of magnetic particle imaging

Kuan Lu, Patrick Goodwill, Bo Zheng, Steven Conolly

Proceedings Volume 7965, 79652I (2011) https://doi.org/10.1117/12.878446

KEYWORDS: Image filtering, Particles, Electronic filtering, Image restoration, Linear filtering, Magnetism, Magnetic particle imaging, Nanoparticles, Signal attenuation, Spatial frequencies

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Magnetic particle imaging (MPI) is a new medical imaging modality that maps the instantaneous response of superparamagnetic particles under an applied magnetic field. In MPI, the excitation and detection of the nanoparticles occur simultaneously. Therefore, when a sinusoidal excitation field is applied to the system, the received signal spectrum contains both harmonics from the particles and a direct feedthrough signal from the source at the fundamental drive frequency. Removal of the induced feedthrough signal from the received signal requires significant filtering, which also removes part of the signal spectrum. In this paper, we present a method to investigate the impact of temporally filtering out individual lower order harmonics on the reconstructed x-space image. Analytic and simulation results show that the loss of particle signal at low frequency leads to a recoverable loss of low spatial frequency information in the x-space image. Initial experiments validate the findings and demonstrate the feasibility of the recovery of the lost signal. This builds on earlier work that discusses the ideal one-dimensional MPI system and harmonic decomposition of the MPI signal.

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