Dr. Julia Mikhal Profile

Dr. Julia Mikhal

at Univ Twente

SPIE Involvement:

Author

Publications (3)

SPIE Journal Paper | 13 January 2021 Open Access

In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

Astrid Hoving, Jason Voorneveld, Julia Mikhal, Johan Bosch, Erik Groot Jebbink, Cornelis Slump

JMI, Vol. 8, Issue 01, 017001, (January 2021) https://doi.org/10.1117/12.10.1117/1.JMI.8.1.017001

KEYWORDS: Ultrasonography, In vitro testing, Arteries, Blood circulation, Statistical analysis, In vivo imaging, Blood, Velocity measurements, Particle image velocimetry, Metals

Read Abstract +

DOWNLOAD PAPER

Proceedings Article | 8 March 2019 Paper

Fully resolved simulation and ultrasound flow studies in stented carotid aneurysm model

J. Mikhal, A. Hoving, G. Ong, C. Slump

Proceedings Volume 10951, 1095115 (2019) https://doi.org/10.1117/12.2513002

KEYWORDS: Aneurysms, 3D modeling, Ultrasonography, Process modeling, Arteries, Numerical simulations, Blood circulation, Computer simulations, In vitro testing, Visualization

Read Abstract +

Introduction. Treatment choice for extracranial carotid artery widening, also called aneurysm, is difficult. Blood flow simulation and experimental visualization can be supportive in clinical decision making and patient-specific treatment prediction. This study aims to simulate and validate the effect of flow-diverting stent placement on blood flow characteristics using numerical and in vitro simulation techniques in simplified carotid artery and aneurysm models. Methods. We have developed a workflow from geometry design to flow simulations and in vitro measurements in a carotid aneurysm model. To show feasibility of the numerical simulation part of the workflow that uses an immersed boundary method, we study a model geometry of an extracranial carotid artery aneurysm and put a flow-diverting stent in the aneurysm. We use ultrasound particle image velocimetry (PIV) to visualize experimentally the flow inside the aneurysm model. Results. Feasibility of ultrasound visualization of the flow, virtual flow-diverting stent placement and numerical flow simulation are presented. Flow is resolved to scales much smaller than the cross section of individual wires of the flow-diverting stent. Numerical analysis in stented model introduced 25% reduction of the blood flow inside the aneurysm sac. Quantitative comparison of experimental and numerical results showed agreement in 1D velocity profiles. Discussion/conclusion. We find good numerical convergence of the simulations at appropriate spatial resolutions using the immersed boundary method. This allows us to quantify the changes in the flow in model geometries after deploying a flow-diverting stent. We visualized the physiological blood flow in a 1-to-1 aneurysm model, using PIV, showing a good correspondence to the numerical simulations. The novel workflow enables numerical as well as experimental flow simulations in patient-specific cases before and after flow-diverting stent placement. This may contribute to endovascular treatment prediction.

Proceedings Article | 6 March 2018 Paper

In vitro high-frame-rate contrast-enhanced ultrasound particle image velocimetry in a carotid artery stent

Astrid Hoving, Jason Voorneveld, Evelien de Vries, Erik Groot Jebbink, Michel Versluis, Johan Bosch, Nico de Jong, Julia Mikhal, Gert de Borst, Cornelis Slump

Proceedings Volume 10580, 105800A (2018) https://doi.org/10.1117/12.2293669

KEYWORDS: Ultrasonography, Arteries, In vitro testing, Numerical simulations, Silicon, Transducers, Particle image velocimetry, Blood circulation, Velocity measurements, Computer simulations

Read Abstract +

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years