We present a miniature motorized endoscopic probe for Optical Frequency Domain Imaging with an outer diameter of
1.65 mm and a rotation speed of 3,000 – 12,500 rpm. The probe has a motorized distal end which provides a significant
advantage over proximally driven probes since it does not require a drive shaft to transfer the rotational torque to the
distal end of the probe and functions without a fiber rotary junction. The probe has a focal Full Width at Half Maximum
of 9.6 μm and a working distance of 0.47 mm. We analyzed the non-uniform rotation distortion and found a location
fluctuation of only 1.87° in repeated measurements of the same object. The probe was integrated in a high-speed Optical
Frequency Domain Imaging setup at 1310 nm. We demonstrated its performance with imaging ex vivo pig bronchial and
in vivo goat lung.
We present a miniature motorized endoscopic probe for Optical Frequency Domain Imaging with an outer diameter of 1.65 mm and a rotation speed of 3,000 – 12,500 rpm. This is the smallest motorized high speed OCT probe to our knowledge. The probe has a motorized distal end which provides a significant advantage over proximally driven probes since it does not require a drive shaft to transfer the rotational torque to the distal end of the probe and functions without a fiber rotary junction. The probe has a focal Full Width at Half Maximum of 9.6 μm and a working distance of 0.47 mm. We analyzed the non-uniform rotation distortion and found a location fluctuation of only 1.87° in repeated measurements of the same object. The probe was integrated in a high-speed Optical Frequency Domain Imaging setup at 1310 nm We demonstrated its performance with imaging ex vivo pig bronchial and in vivo goat lung.
Phase-resolved optical frequency domain imaging (OFDI) has emerged as a promising technique for blood flow
measurement in human tissues. Phase stability is essential for this technique to achieve high accuracy in flow velocity
measurement. In OFDI systems that use k-clocking for the data acquisition, phase-error occurs due to jitter in the data
acquisition electronics. We presented a statistical analysis of jitter represented as point shifts of the k-clocked spectrum.
We demonstrated a real-time phase-error correction algorithm for phase-resolved OFDI. A 50 KHz wavelength-swept
laser (Axsun Technologies) based balanced-detection OFDI system was developed centered at 1310 nm. To evaluate the
performance of this algorithm, a stationary gold mirror was employed as sample for phase analysis. Furthermore, we
implemented this algorithm for imaging of human skin. Good-quality skin structure and Doppler image can be observed
in real-time after phase-error correction. The results show that the algorithm can effectively correct the jitter-induced
phase error in OFDI system.
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