Capabilities to structure X-ray light are developing fast and now allow to generate and characterize light carrying orbital angular momentum (OAM). The use of X-rays to design novel spectroscopic signals sensitive to molecular chirality will be presented. Their differences and similarities with optical techniques will be briefly outlined and we then introduce X-ray helical dichroism, the dichroic measurement of absorption spectra with positive and negative OAM. An experimental implementation of helical dichroism developed at the Swiss Light Source (SLS) synchrotron using spiral Fresnel zoneplates on iron chiral complexes will be discussed.
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