Dr. Ivan V. Lopushenko Profile

Dr. Ivan V. Lopushenko

Postdoctoral Researcher

SPIE Involvement:

Author

Area of Expertise:

numerical simulations , mathematical physics , electrodynamics , biophotonics , Monte Carlo , Discrete Sources Method

Publications (5)

SPIE Journal Paper | 21 November 2023 Open Access

Exploring the evolution of circular polarized light backscattered from turbid tissue-like disperse medium utilizing generalized Monte Carlo modeling approach with a combined use of Jones and Stokes–Mueller formalisms

Ivan Lopushenko, Oleksii Sieryi, Alexander Bykov, Igor Meglinski

JBO, Vol. 29, Issue 05, 052913, (November 2023) https://doi.org/10.1117/12.10.1117/1.JBO.29.5.052913

KEYWORDS: Polarization, Polarized light, Sensors, Turbidity, Mueller matrices, Light scattering, Scattering, Tissues, Depolarization, Monte Carlo methods

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SignificancePhase retardation of circularly polarized light (CPL), backscattered by biological tissue, is used extensively for quantitative evaluation of cervical intraepithelial neoplasia, presence of senile Alzheimer’s plaques, and characterization of biotissues with optical anisotropy. The Stokes polarimetry and Mueller matrix approaches demonstrate high potential in definitive non-invasive cancer diagnosis and tissue characterization. The ultimate understanding of CPL interaction with tissues is essential for advancing medical diagnostics, optical imaging, therapeutic applications, and the development of optical instruments and devices.AimWe investigate propagation of CPL within turbid tissue-like scattering medium utilizing a combination of Jones and Stokes–Mueller formalisms in a Monte Carlo (MC) modeling approach. We explore the fundamentals of CPL memory effect and depolarization formation.ApproachThe generalized MC computational approach developed for polarization tracking within turbid tissue-like scattering medium is based on the iterative solution of the Bethe–Salpeter equation. The approach handles helicity response of CPL scattered in turbid medium and provides explicit expressions for assessment of its polarization state.ResultsEvolution of CPL backscattered by tissue-like medium at different conditions of observation in terms of source–detector configuration is assessed quantitatively. The depolarization of light is presented in terms of the coherence matrix and Stokes–Mueller formalism. The obtained results reveal the origins of the helicity flip of CPL depending on the source–detector configuration and the properties of the medium and are in a good agreement with the experiment.ConclusionsBy integrating Jones and Stokes–Mueller formalisms, the combined MC approach allows for a more complete representation of polarization effects in complex optical systems. The developed model is suitable to imitate propagation of the light beams of different shape and profile, including Gaussian, Bessel, Hermite–Gaussian, and Laguerre–Gaussian beams, within tissue-like medium. Diverse configuration of the experimental conditions, coherent properties of light, and peculiarities of polarization can be also taken into account.

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SPIE Journal Paper | 14 November 2023 Open Access

Incremental residual polarization caused by aging in human skin

Viktor Dremin, Elena Zharkikh, Ivan Lopushenko, Zbignevs Marcinkevics, Alexander Bykov, Igor Meglinski

JBO, Vol. 29, Issue 05, 052912, (November 2023) https://doi.org/10.1117/12.10.1117/1.JBO.29.5.052912

KEYWORDS: Polarization, Skin, Scattering, Tissues, Absorption, Light scattering, Collagen, Polarized light, Blood, Optical properties

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Proceedings Article | 5 October 2023 Presentation

Optical biopsy and biomedical diagnosis with circular polarisation and orbital angular momentum of light

Igor Meglinski, Ivan Lopushenko, Anton Sdobnov, Alexander Bykov

Proceedings Volume PC12690, PC1269004 (2023) https://doi.org/10.1117/12.2674384

KEYWORDS: Biomedical optics, Polarized light, Polarization, Angular momentum, Tissues, Biopsy, Tissue optics, Light scattering, Laser scattering, Depolarization

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