Ms. Haiqiu Yang Profile

Haiqiu Yang

SPIE Involvement:

Author | Student Chapter President

Publications (12)

Proceedings Article | 13 March 2024 Presentation

High density optical substrate mapping of the left atrium with near infrared spectroscopy

Haiqiu Yang, Jonah Majumder, Ziyi Huang, Kenneth Laurita, Andrew Rollins, Christine Hendon

Proceedings Volume 12819, 128190S (2024) https://doi.org/10.1117/12.3002814

KEYWORDS: Near infrared spectroscopy, Tissue optics, Spectral density, Blood, Absorbance, Radio optics, Atrial fibrillation, Visualization, Tissues, Radiofrequency ablation

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Proceedings Article | 13 March 2024 Presentation

Catheter-based diffuse reflectance spectroscopy for cardiac substrate mapping

Jonah Majumder, Haiqiu Yang, Ziyi Huang, Aidan Therien, Kenneth Laurita, Andrew Rollins, Deepak Saluja, Christine Hendon

Proceedings Volume PC12836, PC128360B (2024) https://doi.org/10.1117/12.3001935

KEYWORDS: Diffuse reflectance spectroscopy, Tissues, Radiofrequency ablation, Atrial fibrillation, Ablation, Tissue optics, Reflectivity, Photons, Biological samples, Spectroscopy

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Proceedings Article | 13 March 2024 Presentation + Paper

PSOCT, NIRS, and optical mapping of low voltage zones in atrial fibrillation

Michael Douglass, Lydia Akino, Juan Perez, Haiqiu Yang, Jonah Majumder, Walter Hoyt, Ohad Ziv, Kenneth Laurita, Christine Hendon, Andrew Rollins

Proceedings Volume 12819, 128190R (2024) https://doi.org/10.1117/12.3001724

KEYWORDS: Atrial fibrillation, Near infrared spectroscopy, Tissues, Ablation, In vivo imaging, Tissue optics, Heart, Birefringence, Veins, Pathology

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Atrial fibrillation (AF) is the most common arrhythmia worldwide. An increasingly common treatment option is catheter ablation. During this procedure, the clinician steers a catheter into the left atrium and ablates a lesion fence around the pulmonary veins, a common source of ectopic signals. This lesion fence blocks arrhythmogenic tissue from initiating an erroneous heartbeat. However, if the disease has progressed from paroxysmal to persistent, pathogenic tissue exists throughout the atrium, and common ablation schemes are not as effective. In this case, technologies exist to electroanatomically map the atrium and guide clinicians in targeting adjunctive AF ablation targets. Low voltages mapped in vivo are a well-documented way of identifying atrial fibrosis, an important substrate for AF. Ablating low voltage zones in patients with a more developed disease can help terminate AF and improve long-term outcomes, but low voltage measurements are not specific to fibrosis. Treatment results vary because the targeting that electroanatomical mapping provides is incomplete. Our group has shown that polarization-sensitive optical coherence tomography (PSOCT) and near infrared spectroscopy (NIRS) can monitor lesion formation in vivo and differentiate tissue types in the atrium. Now, we are investigating the technology’s utility in identifying AF targets prior to ablation. We have collaborated in developing a swine model of AF that shows the atria remodels during the diseased state. Because of this, we can electroanatomically map these diseased hearts in vivo to measure low voltage zones. Subsequently, we examine the left atrium ex vivo using benchtop PSOCT, NIRS, and optical mapping (OM) and register these optical measurements to the in vivo low voltage zones. We show that OM confirms abnormal conduction, while PSOCT- and NIRS-derived metrics have promise for identifying low voltage zones. We confirm these measures with histological identification of fibrosis. This suggests the feasibility of using PSOCT-NIRS at the catheter tip to detect AF ablation targets.

SPIE Journal Paper | 28 February 2024 Open Access

Robust, high-density lesion mapping in the left atrium with near-infrared spectroscopy

Haiqiu Yang, Jonah Majumder, Ziyi Huang, Deepak Saluja, Kenneth Laurita, Andrew Rollins, Christine Hendon

JBO, Vol. 29, Issue 02, 028001, (February 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.2.028001

KEYWORDS: Tissues, Blood, Near infrared spectroscopy, Tissue optics, Radiofrequency ablation, Heart, Ablation, Data modeling, Education and training, Reflectivity

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Proceedings Article | 17 March 2023 Presentation

Multi-modal imaging system with optically integrated probe for left atrial anatomical mapping

Haiqiu Yang, Michael Douglass, Deepak Saluja, Kenneth Laurita, Andrew Rollins, Christine Hendon

Proceedings Volume PC12355, PC1235507 (2023) https://doi.org/10.1117/12.2650336

KEYWORDS: System integration, Radiofrequency ablation, Multimodal imaging, Integrated optics, Imaging systems, Tissues, Radio optics, Optical coherence tomography, Near infrared spectroscopy, Blood

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Proceedings Article | 14 March 2023 Presentation + Paper

Polarization-Sensitive Optical Coherence Tomography (PSOCT) for identifying and analyzing gaps in lesion lines during ex vivo simulated radiofrequency ablation procedure

Michael Douglass, Juan Perez, Lydia Akino, Haiqiu Yang, Walter Hoyt, Ohad Ziv, Kenneth Laurita, Christine Hendon, Andrew Rollins

Proceedings Volume 12355, 1235503 (2023) https://doi.org/10.1117/12.2650838

KEYWORDS: Ablation, Tissues, Atrial fibrillation, Radiofrequency ablation, Polarization, Birefringence, Optical coherence tomography

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Proceedings Article | 6 March 2023 Presentation

Optical coherence tomography enabled tissue architecture characterization of uterine tumors

Arielle Joasil, Haiqiu Yang, Hanina Hibshoosh, Christine Hendon

Proceedings Volume PC12368, PC1236809 (2023) https://doi.org/10.1117/12.2650591

KEYWORDS: Tumors, Optical coherence tomography, Tissues, Tissue optics, Uterus, Surgery, Collagen, Analytical research

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Proceedings Article | 7 March 2022 Presentation

Cardiac endocardial left atrial substrate mapping and lesion depth assessment using near-infrared spectroscopy

Soo Young Park, Haiqiu Yang, Charles Marboe, Ohad Ziv, Kenneth Laurita, Andrew Rollins, Deepak Saluja, Christine Hendon

Proceedings Volume PC11936, PC1193609 (2022) https://doi.org/10.1117/12.2610367

KEYWORDS: Near infrared spectroscopy, Veins, Associative arrays, Tissue optics, Tissues, Systems modeling, Spectroscopy, Natural surfaces, Heart, Diffuse reflectance spectroscopy

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Proceedings Article | 7 March 2022 Presentation

Lesion gap assessment in left atrium by spectroscopic anatomical mapping with optically integrated catheter

Haiqiu Yang, Soo Young Park, Christine Hendon

Proceedings Volume PC11936, PC1193605 (2022) https://doi.org/10.1117/12.2608293

KEYWORDS: Near infrared spectroscopy, Spectroscopy, Integrated optics, Radiofrequency ablation, Radio optics, Heart, Atrial fibrillation, Veins, Tissue optics, Reflectivity

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Proceedings Article | 5 March 2021 Presentation

Spectroscopic anatomical mapping of left atrium endocardial substrate and lesion using an optically integrated mapping catheter

Soo Young Park, Rajinder Singh-Moon, Haiqiu Yang, Amardeep Saluja, Christine Hendon

Proceedings Volume 11621, 1162104 (2021) https://doi.org/10.1117/12.2578520

KEYWORDS: Spectroscopy, Tissues, Near infrared spectroscopy, Integrated optics, Atrial fibrillation, Radio optics, Associative arrays, Reconstruction algorithms, Radiofrequency ablation, Algorithm development

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Proceedings Article | 5 March 2021 Presentation

Irrigated cardiac endocardial lesion assessment using single fiber-multispectral spectroscopy and neural networks

Soo Young Park, Haiqiu Yang, Rajinder Singh-Moon, Amardeep Saluja, Christine Hendon

Proceedings Volume 11621, 1162103 (2021) https://doi.org/10.1117/12.2578506

KEYWORDS: Neural networks, Spectroscopy, Radiofrequency ablation, Tissue optics, Optical spectroscopy, Tissues, Thermography, Temperature metrology, Light sources, In vivo imaging

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Proceedings Article | 5 March 2021 Presentation

In-vivo demonstration of irrigated lesion morphology using near-infrared spectroscopy and artificial neural networks

Soo Young Park, Rajinder Singh-Moon, Haiqiu Yang, Vivek Iyer, Amardeep Saluja, Christine Hendon

Proceedings Volume 11631, 1163107 (2021) https://doi.org/10.1117/12.2578483

KEYWORDS: Near infrared spectroscopy, In vivo imaging, Artificial neural networks, Radiofrequency ablation, Tissues, Atrial fibrillation, Tissue optics, Spectroscopy, Optical spectroscopy

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Showing 5 of 12 publications

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