Open Access
2 February 2017 Simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography, part 2: implementation
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Abstract
We introduce a theoretical method for simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography (FD-OCT) without any auxiliary arrangement. The input data to the formalism are the FD-OCT measured optical path lengths (OPLs) and properly selected spectral components of FD-OCT interference spectrum. The outputs of the formalism can be affected significantly by uncertainty in measuring the OPLs. An optimization method is introduced to deal with the relatively large amount of uncertainty in measured OPLs and enhance the final results. Simulation result shows that by using the optimization method, indices can be extracted with the absolute error 0.001 for transparent biological samples having indices <1.55.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2017/$25.00 © 2017 SPIE
Payman Rajai, Henry Schriemer, Ahmad Amjadi, and Rejean Munger "Simultaneous measurement of refractive index and thickness of multilayer systems using Fourier domain optical coherence tomography, part 2: implementation," Journal of Biomedical Optics 22(1), 015003 (2 February 2017). https://doi.org/10.1117/1.JBO.22.1.015003
Received: 17 October 2016; Accepted: 3 January 2017; Published: 2 February 2017
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CITATIONS
Cited by 7 scholarly publications.
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KEYWORDS
Refractive index

Optical coherence tomography

Received signal strength

Optical testing

Error analysis

Refraction

Data modeling

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