Automatic sound speed selection in photoacoustic image reconstruction using an autofocus approach

Bradley E. Treeby; Trond K. Varslot; Edward Z. Zhang; Jan G. Laufer; Paul C. Beard

doi:10.1117/1.3619139

1 September 2011 Automatic sound speed selection in photoacoustic image reconstruction using an autofocus approach

Bradley E. Treeby, Trond K. Varslot, Edward Z. Zhang, Jan G. Laufer, Paul C. Beard

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Journal of Biomedical Optics, Vol. 16, Issue 9, 090501 (September 2011). https://doi.org/10.1117/1.3619139

Abstract

The reconstruction of images in photoacoustic tomography is reliant on specifying the speed of sound within the propagation medium. However, for in vivo imaging, this value is not normally accurately known. Here, an autofocus approach for automatically selecting the sound speed is proposed. This is based on maximizing the sharpness of the reconstructed image as quantified by a focus function. Several focus functions are investigated, and their performance is discussed. The method is demonstrated using phantom measurements made in a medium with a known sound speed and in vivo measurements of the vasculature in the flank of an adult mouse.

©(2011) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Bradley E. Treeby, Trond K. Varslot, Edward Z. Zhang, Jan G. Laufer, and Paul C. Beard "Automatic sound speed selection in photoacoustic image reconstruction using an autofocus approach," Journal of Biomedical Optics 16(9), 090501 (1 September 2011). https://doi.org/10.1117/1.3619139

Published: 1 September 2011

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