Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment

Clement Yuen; Wei Zheng; Zhiwei Huang

doi:10.1117/1.3050447

1 November 2008 Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment

Clement Yuen, Wei Zheng, Zhiwei Huang

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Journal of Biomedical Optics, Vol. 13, Issue 6, 064040 (November 2008). https://doi.org/10.1117/1.3050447

Abstract

We report a novel postgrowth microwave heating implementation by selectively modifying hierarchical polystyrene (PS) bead substrates coated with gold (Au) films to effectively improve the surface-enhanced Raman scattering (SERS) effect on the analytes. The SERS signal of probe molecule rhodamine 6G (Rh 6G) on the microwave-treated Au–PS substrates can be improved by 10-fold, while the detection limit of Rh 6G in concentration can be enhanced by two orders of magnitude compared to the as-growth substrates. The high-quality SERS spectrum of saliva can also be acquired using the modified substrates, demonstrating the potential for the realization of the high-performance SERS substrates for biomedical applications.

©(2008) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Clement Yuen, Wei Zheng, and Zhiwei Huang "Improving surface-enhanced Raman scattering effect using gold-coated hierarchical polystyrene bead substrates modified with postgrowth microwave treatment," Journal of Biomedical Optics 13(6), 064040 (1 November 2008). https://doi.org/10.1117/1.3050447

Published: 1 November 2008

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KEYWORDS

Gold

Picosecond phenomena

Microwave radiation

Medium wave

Raman scattering

Surface enhanced Raman spectroscopy

Rhodium

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