Non-invasive zinc protoporphyrin screening offers opportunities for secondary prevention of iron deficiency in blood donors

Ronald Sroka; Anne Schliemann; Max Eisel; Herbert Stepp; Michael Vogeser; Ernst-Markus Quenzel; Christian Homann; Max Aumiller; Adrian Rühm

doi:10.1117/12.3022798

20 June 2024 Non-invasive zinc protoporphyrin screening offers opportunities for secondary prevention of iron deficiency in blood donors

Ronald Sroka, Anne Schliemann, Max Eisel, Herbert Stepp, Michael Vogeser, Ernst-Markus Quenzel, Christian Homann, Max Aumiller, Adrian Rühm

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Proceedings Volume PC13008, Biophotonics in Point-of-Care III; PC130080D (2024) https://doi.org/10.1117/12.3022798
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Conference Poster

Abstract

Frequent blood donors are therefore at an increased risk of developing iron deficiency. Currently, there is no easy and routinely available method during blood donation to detect iron deficient erythropoiesis (IDE) before the amount of healthy red blood cells drops below normal levels, which is referred to as anemia. An optical technology to detect iron deficiency in a pre-anemic state had been developed. The measurement is performed on the tubing between the donor and the blood collection bag during the donation. The measurement takes about 1 minute and provides an immediate result at very low costs. The evaluation showed a high sensitivity to identify blood donors with advanced iron deficiency before anemia occurs. The method was shown to be more sensitive than the standard assessment of the hemoglobin value. The optical method envisioned the feasibility and diagnostic value to prevent iron deficiency anemia of frequent blood donors by providing an early warning signal. Beyond the health benefit for the blood donor, this might also lead to less rejections of blood donors due to iron deficiency anemia.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

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Ronald Sroka, Anne Schliemann, Max Eisel, Herbert Stepp, Michael Vogeser, Ernst-Markus Quenzel, Christian Homann, Max Aumiller, and Adrian Rühm "Non-invasive zinc protoporphyrin screening offers opportunities for secondary prevention of iron deficiency in blood donors", Proc. SPIE PC13008, Biophotonics in Point-of-Care III, PC130080D (20 June 2024); https://doi.org/10.1117/12.3022798

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