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13 March 2024 Computational stimulated Raman scattering imaging
Haonan Lin, Ji-Xin Cheng
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Proceedings Volume PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024; PC128550O (2024) https://doi.org/10.1117/12.3001771
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Label-free chemical imaging by stimulated Raman scattering (SRS) has seen rapid developments and widespread biomedical applications. Nevertheless, the cross-section of the Raman process sets up a physical limit that impedes further evolution of SRS. Computational imaging is an appealing approach to break the physical barrier through the synergistic integration of advanced instrumentation and data science. In this talk, I will introduce a series of computational SRS work to push the physical limits in the aspects of imaging speed, signal fidelity, chemical specificity, and spatial resolution.
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Haonan Lin and Ji-Xin Cheng "Computational stimulated Raman scattering imaging", Proc. SPIE PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, PC128550O (13 March 2024); https://doi.org/10.1117/12.3001771
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KEYWORDS
Imaging spectroscopy
Raman scattering
Biomedical optics
Chemical analysis
Matrices
Medical research
Spatial resolution
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