Improving oral cancer surgery by intra-operative assessment of resection margins: need for objective techniques

Senada Koljenovic M.D.; Gerwin Puppels

doi:10.1117/12.3025020

13 March 2024 Improving oral cancer surgery by intra-operative assessment of resection margins: need for objective techniques

Senada Koljenovic M.D., Gerwin Puppels

Author Affiliations +

Proceedings Volume PC12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis; PC128360F (2024) https://doi.org/10.1117/12.3025020
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Patients with oral cavity cancer are often treated with surgery. The goal is to remove the tumor with a margin of > 5 mm of surrounding healthy tissue. Unfortunately, this is only achieved in about 15% to 26% of cases. Intraoperative assessment of tumor resection margins can dramatically improve surgical results. However, current methods are laborious, subjective, and logistically demanding. This hinders broad adoption of IOARM, to the detriment of patients. Therefore, an objective easy-to-use technique is needed, to accurately assess all resection margins intraoperatively. The role of photonic techniques in general will be discussed and the development of a high-wavenumber Raman spectroscopic technology, for quick and objective intraoperative measurement of resection margins will be presented.

Conference Presentation

Citation Download Citation

Senada Koljenovic M.D. and Gerwin Puppels "Improving oral cancer surgery by intra-operative assessment of resection margins: need for objective techniques", Proc. SPIE PC12836, Optical Biopsy XXII: Toward Real-Time Spectroscopic Imaging and Diagnosis, PC128360F (13 March 2024); https://doi.org/10.1117/12.3025020

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