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13 March 2024 Epivascular microstructures investigated by pyramid wavefront sensor-based AO-OCT
Elisabeth Brunner, Laura Kunze, Victoria Hutterer, Daniel Jodlbauer, Wolfgang Drexler, Ronny Ramlau, Andreas Pollreisz, Michael Pircher
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Proceedings Volume PC12824, Ophthalmic Technologies XXXIV; PC1282405 (2024) https://doi.org/10.1117/12.3005620
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Epivascular microstructures, a potential biomarker for retinal diseases, are investigated in the living human retina using adaptive optics optical coherence tomography (AO-OCT). The AO correction is driven by a four-sided pyramid wavefront sensor with a loop bandwidth of 30 Hz. In order to achieve a stable placement of the focus of the imaging beam in the desired retinal layer, a new concept for focus shifting is introduced which uses an in vivo calibration routine that is performed pre-imaging in each subject. The capability of the instrument is demonstrated by visualizing hyporeflective microstructures situated along the retinal vasculature with single volume AO-OCT images recorded at an extended 4° x 4° field of view.
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Elisabeth Brunner, Laura Kunze, Victoria Hutterer, Daniel Jodlbauer, Wolfgang Drexler, Ronny Ramlau, Andreas Pollreisz, and Michael Pircher "Epivascular microstructures investigated by pyramid wavefront sensor-based AO-OCT", Proc. SPIE PC12824, Ophthalmic Technologies XXXIV, PC1282405 (13 March 2024); https://doi.org/10.1117/12.3005620
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KEYWORDS
Adaptive optics optical coherence tomography
Wavefront sensors
Adaptive optics
Retina
Visualization
Reflection
Retinal scanning
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