The NV-biosensor and the use of diamond magnetometry to detect stress biomarkers in artificial saliva

Arfaan A. Rampersaud; Isaac V. Rampersaud; Charles Fletcher; Michael Slocum; Michael Wolf; Lawrence Drummy; Daniel Long

doi:10.1117/12.2664271

14 June 2023 The NV-biosensor and the use of diamond magnetometry to detect stress biomarkers in artificial saliva

Arfaan A. Rampersaud, Isaac V. Rampersaud, Charles Fletcher, Michael Slocum, Michael Wolf, Lawrence Drummy, Daniel Long

Proceedings Volume PC12541, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XXIV; PC125410E (2023) https://doi.org/10.1117/12.2664271
Event: SPIE Defense + Commercial Sensing, 2023, Orlando, Florida, United States

Conference Poster

Abstract

The NV-Biosensor uses a fluorescent nitrogen-vacancy center nanodiamond and diamond magnetometry to detect biological targets with high sensitivity. It can be designed to sense nucleic acid or protein biomarkers that are indicative of physiologic conditions, such as viral infection, chem-bio exposure, stress levels, cardiac distress, and even cancer markers. Once fully developed, the NV-Biosensor can be used to continuously monitor Warfighters for their well-being while in the field. We describe our preliminary results to create an NV-Biosensor that can detect nucleic acid biomarkers of stress and include a description of our optical set-up, biochemical methods, bioconjugation strategies and preliminary results.

Citation Download Citation

Arfaan A. Rampersaud, Isaac V. Rampersaud, Charles Fletcher, Michael Slocum, Michael Wolf, Lawrence Drummy, and Daniel Long "The NV-biosensor and the use of diamond magnetometry to detect stress biomarkers in artificial saliva", Proc. SPIE PC12541, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XXIV, PC125410E (14 June 2023); https://doi.org/10.1117/12.2664271

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