Experimental demonstration of nonlinear chiroptical scattering after its prediction 40 years ago (Conference Presentation)

Ventsislav K. Valev

doi:10.1117/12.2646816

17 March 2023 Experimental demonstration of nonlinear chiroptical scattering after its prediction 40 years ago (Conference Presentation)

Ventsislav K. Valev

Author Affiliations +

Proceedings Volume PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII; PC1239508 (2023) https://doi.org/10.1117/12.2646816
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Current drug discovery is facing numerous challenges: antimicrobial resistance, increased risk of future pandemics from globalization, spiralling costs of new drugs, etc. High-throughput (HT) synthesis with robotized operations driven by AI algorithms could help to accelerate drug discovery and development, but it requires miniaturized sample volumes. The majority of new drugs entering the market are chiral. Therefore, new experimental tools are needed to probe chirality in tiny volumes. Solving a 40-years old scientific question, our team reported a new chiral optical effect that probes chirality in tiny volumes across a range of inorganic nanoparticles, randomly distributed in isotropic liquids.

Conference Presentation

Citation Download Citation

Ventsislav K. Valev "Experimental demonstration of nonlinear chiroptical scattering after its prediction 40 years ago (Conference Presentation)", Proc. SPIE PC12395, Colloidal Nanoparticles for Biomedical Applications XVIII, PC1239508 (17 March 2023); https://doi.org/10.1117/12.2646816

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