Integrated spectral interrogator for point-of-care biosensors

Anne van Klinken; Ruud Jansen; Arthur Hendriks; Chenhui Li; Mathias Dolci; Petar Sevo; Luca Picelli; Mildred S. Cano-Velázquez; Peter Zijlstra; Andrea Fiore

doi:10.1117/12.2649821

30 March 2023 Integrated spectral interrogator for point-of-care biosensors

Anne van Klinken, Ruud Jansen, Arthur Hendriks, Chenhui Li, Mathias Dolci, Petar Sevo, Luca Picelli, Mildred S. Cano-Velázquez, Peter Zijlstra, Andrea Fiore

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Proceedings Volume PC12387, Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics; PC123870B (2023) https://doi.org/10.1117/12.2649821
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We demonstrate a compact interrogation method for resonance-based biosensors, based on an integrated photonic chip with an array of resonant-cavity enhanced photodetectors. Due to the high signal-to-noise ratio, wavelength shifts in the 10 pm range can be measured, orders of magnitude smaller than the sensor and interrogator linewidths. This approach allows the read-out of resonance-based optical biosensors with simple integrated components, potentially enabling compact and low-cost sensing systems for point-of-care diagnostics.

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Anne van Klinken, Ruud Jansen, Arthur Hendriks, Chenhui Li, Mathias Dolci, Petar Sevo, Luca Picelli, Mildred S. Cano-Velázquez, Peter Zijlstra, and Andrea Fiore "Integrated spectral interrogator for point-of-care biosensors", Proc. SPIE PC12387, Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics, PC123870B (30 March 2023); https://doi.org/10.1117/12.2649821

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KEYWORDS

Biosensors

Point-of-care devices

Sensors

Biological research

Biosensing

Receptors

Reflection

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