Laser speckle contrast imaging (LSCI) is an imaging technique using a speckle pattern randomly produced on the image sensor based on the high coherency light source. LSCI is widely used for biological and clinical diagnoses such as blood flow measurement due to the advantages of real-time imaging, simplicity, and non-invasive. And due to the absorbance characteristics of hemoglobin, if two or more wavelengths in a specific near-infrared region are used, the change in concentration of each oxide, and reduced hemoglobin can be measured. In this study, by combining these two methods, using these systems, blood perfusion and hemodynamic responses in the body were measured in a large area.
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