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There is increased interest in use of multiple optical imaging/sensing modalities together as a means to potentially improve diagnostic outcomes. This presentation will review aspects of analysis methods that have been employed when evaluating diagnostic potential of multimodal imaging. It will include discussion of our own current/previous approaches and a thorough commentary on the methods employed in the literature with literature review focusing on multimodal diagnostic imaging. This review includes investigational as well as clinical modalities, and beyond optical imaging to other modalities. Strategies and specific recommendations for consideration of analyses during the development of multimodal approaches will be presented.
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Paula Villarreal, Suimin Qiu M.D., Xingde Li, Rongguang Liang, Gracie Vargas, "Analysis considerations for multimodal based approaches in diagnostics," Proc. SPIE PC12370, Design and Quality for Biomedical Technologies XVI, PC1237008 (6 March 2023); https://doi.org/10.1117/12.2657771