Multi-resolution three-dimensional mouse tissue imaging with optical coherence tomography and optical coherence microscopy integrated surgical microscope

Myungju Kim; Yujin Ahn; Eunji Lee; Sangjin Lee; Inwoo Park; Joo Beom Eom; Shin Yoo Kyoung; Woonggyu Jung

doi:10.1117/12.2650960

6 March 2023 Multi-resolution three-dimensional mouse tissue imaging with optical coherence tomography and optical coherence microscopy integrated surgical microscope

Myungju Kim, Yujin Ahn, Eunji Lee, Sangjin Lee, Inwoo Park, Joo Beom Eom, Shin Yoo Kyoung, Woonggyu Jung

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Proceedings Volume PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI; PC123680A (2023) https://doi.org/10.1117/12.2650960
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Surgical microscopes provide clear visualization of the tissue and have been increasingly used in operating rooms. Going further from this, we developed optical coherence tomography (OCT), and optical coherence microscopy (OCM) integrated surgical microscope to offer superficial and sub-surface tissue information simultaneously. With the use of an optical switch, OCT and OCM view can be freely converted. After surgical resection of cancer with the guidance of OCT, we performed high-resolution whole cancer imaging with OCM for margin detection. Our proposed system can be a promising tool for intraoperative applications and increase the accuracy of the operation.

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Myungju Kim, Yujin Ahn, Eunji Lee, Sangjin Lee, Inwoo Park, Joo Beom Eom, Shin Yoo Kyoung, and Woonggyu Jung "Multi-resolution three-dimensional mouse tissue imaging with optical coherence tomography and optical coherence microscopy integrated surgical microscope", Proc. SPIE PC12368, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI, PC123680A (6 March 2023); https://doi.org/10.1117/12.2650960

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KEYWORDS

Optical coherence tomography

Cancer

Microscopes

Optical coherence microscopy

Surgery

Tumors

Tissues

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