Catheter-based polarization sensitive optical coherence tomography with a single input polarization state

Georgia Thomas; Brett E. Bouma; Martin Villiger

doi:10.1117/12.2652908

9 March 2023 Catheter-based polarization sensitive optical coherence tomography with a single input polarization state

Georgia Thomas, Brett E. Bouma, Martin Villiger

Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC1236713 (2023) https://doi.org/10.1117/12.2652908
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Despite promise in early pilot studies, clinical translation of intravascular PS-OCT has been limited by the complexity of incorporating polarization modulation. We present a signal processing pipeline which uses maximum-likelihood estimation to reconstruct the polarization properties of tissue measured with a single input polarization state (SIPS-OCT), enabling polarization-sensitivity with existing intravascular OCT devices. SIPS-OCT estimates both the depth resolved birefringence and optic axis orientation, with excellent qualitative and quantitative comparisons to conventional dual-input state PS-OCT. These results present an encouraging step towards removing barriers to PS-OCT adoption by enabling polarization-sensitivity in existing intravascular OCT systems.

Conference Presentation

Citation Download Citation

Georgia Thomas, Brett E. Bouma, and Martin Villiger "Catheter-based polarization sensitive optical coherence tomography with a single input polarization state", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC1236713 (9 March 2023); https://doi.org/10.1117/12.2652908

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