Phase-sensitive optoretiography is an emerging contrast method to assess the functional activity of retinal neurons in living humans. So far, functional signals were mostly observed in the photoreceptors. However, using full-field swept-source optical coherence tomography, additional signals were measured in the inner plexiform layer (IPL), which are linked to higher neuronal activity. Here, we investigated optoretinography signals for 6 different subjects and analyzed the influence of eye motionand the stability of two phase-evaluation algorithms. Thereby, photorceptor signals were observed in all and IPL signals in 85% of the measurements, with matching basic time courses and spatial signal-distribution for all subjects.
|