Developing a molecular understanding for using Raman spectroscopy to measure tissue hydration

Trevor Voss; Anita Mahadevan-Jansen

doi:10.1117/12.2650898

17 March 2023 Developing a molecular understanding for using Raman spectroscopy to measure tissue hydration

Trevor Voss, Anita Mahadevan-Jansen

Proceedings Volume PC12363, Multiscale Imaging and Spectroscopy IV; PC1236306 (2023) https://doi.org/10.1117/12.2650898
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

There is a need for an accurate, non-invasive, and real-time measurement of physiological hydration, in which we need to directly measure changes in water content and dynamics and changes in its molecular environment. Both sweat at the surface of your skin and deeper tissue properties are easily accessible non-invasively to Raman spectroscopy. Complexities in biomolecular systems require a fundamental understanding of the dynamics present in order to accurately assess changes in hydration using Raman spectroscopy. AIMD simulations will be made to compute changing vibrational spectra corresponding to the major hydration related changes in physiological molecular environments and compared to experiment.

Conference Presentation

Citation Download Citation

Trevor Voss and Anita Mahadevan-Jansen "Developing a molecular understanding for using Raman spectroscopy to measure tissue hydration", Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC1236306 (17 March 2023); https://doi.org/10.1117/12.2650898

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