As a multimodal approach, optical coherence tomography (OCT) and Raman spectroscopy (RS) are combined. The acquired morpho-molecular tissue information is not only used for improved clinical diagnostics, but furthermore for investigation, interpretation and understanding of signal origin during ex-vivo as well as in-vivo investigation. We present co-localized, endoscopically acquired OCT and RS data on bladder cancer biopsies. Ground truth is histopathological examination. These findings contribute to interpretation of in-vivo data acquired with endoscopic imaging systems. This approach not only opens a new way of interpretation of both modalities but enables access to clinical relevant information, which is nowadays not available in-situ.
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