Comparative optoretinography of intrinsic signal amplitude and phase change in the human retina

Guangying Ma; Taeyoon Son; Tae-Hoon Kim; Xincheng Yao

doi:10.1117/12.2609242

7 March 2022 Comparative optoretinography of intrinsic signal amplitude and phase change in the human retina

Guangying Ma, Taeyoon Son, Tae-Hoon Kim, Xincheng Yao

Proceedings Volume PC11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI; PC119481H (2022) https://doi.org/10.1117/12.2609242
Event: SPIE BiOS, 2022, San Francisco, California, United States

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Abstract

This study is to compare the optical coherence tomography (OCT) amplitude intrinsic optical signal (IOS) and phase IOS change of the human retina after light stimulation. A custom constructed OCT was employed for functional optoretinography imaging. A white LED was used as the retinal stimulator. OCT amplitude and phase IOS were computed by comparing the amplitude and phase before and after light stimulation. Both amplitude IOS and phase IOS were observed right after the stimulus onset, predominantly in the outer retina. The phase IOS is more sensitive to the layer boundaries.

Citation Download Citation

Guangying Ma, Taeyoon Son, Tae-Hoon Kim, and Xincheng Yao "Comparative optoretinography of intrinsic signal amplitude and phase change in the human retina", Proc. SPIE PC11948, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVI, PC119481H (7 March 2022); https://doi.org/10.1117/12.2609242

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