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7 March 2022 Functional imaging of rods and cones in the living human eye
Clara Pfäffle, Hendrik Spahr, David Melenberg, Gereon Hüttmann, Dierck Hillmann
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Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC119410D (2022) https://doi.org/10.1117/12.2609679
Event: SPIE BiOS, 2022, San Francisco, California, United States
Abstract
In several retinal pathologies, such as AMD and retinitis pigmentosa, function of cones and rods are affected to different extents. To investigate these, an imaging modality is needed that separates the function of both photoreceptor types. Recently, functional imaging of single cones using phase-sensitive OCT has been demonstrated. However, until now, functional imaging of rods was only possible with high resolution systems. Here we differentiate the functional response of rods and cones without resolving single photoreceptors. After stimulation with short illumination in the mesoscopic range, the different temporal dynamics of rods and cones are distinguished by their typical response characteristics.
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Clara Pfäffle, Hendrik Spahr, David Melenberg, Gereon Hüttmann, and Dierck Hillmann "Functional imaging of rods and cones in the living human eye", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC119410D (7 March 2022); https://doi.org/10.1117/12.2609679
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KEYWORDS
Rods
Cones
Eye
Functional imaging
Optical coherence tomography
Retina
Imaging systems
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